نتایج جستجو برای: radiation mitigation

تعداد نتایج: 270118  

2015
David J Hall Nathan Bush Neil Murray Jason Gow Andrew Clarke Ross Burgon

The Charge Coupled Device (CCD) has a long heritage for imaging and spectroscopy in many space astronomy missions. However, the harsh radiation environment experienced in orbit creates defects in the silicon that capture the signal being transferred through the CCD. This radiation damage has a detrimental impact on the detector performance and requires carefully planned mitigation strategies. T...

2017
Amrita K Cheema Khyati Y Mehta Oluseyi O Fatanmi Stephen Y Wise Charles P Hinzman Josh Wolff Vijay K Singh

The development of radiation countermeasures for acute radiation syndrome (ARS) has been underway for the past six decades, leading to the identification of multiple classes of radiation countermeasures. However, to date, only two growth factors (Neupogen and Neulasta) have been approved by the United States Food and Drug Administration (US FDA) for the mitigation of hematopoietic acute radiati...

2013
Ajay Kapur Gina Goode Catherine Riehl Petrina Zuvic Sherin Joseph Nilda Adair Michael Interrante Beatrice Bloom Lucille Lee Rajiv Sharma Anurag Sharma Jeffrey Antone Adam Riegel Lili Vijeh Honglai Zhang Yijian Cao Carol Morgenstern Elaine Montchal Brett Cox Louis Potters

By combining incident learning and process failure-mode-and-effects-analysis (FMEA) in a structure-process-outcome framework we have created a risk profile for our radiation medicine practice and implemented evidence-based risk-mitigation initiatives focused on patient safety. Based on reactive reviews of incidents reported in our departmental incident-reporting system and proactive FMEA, high ...

2013
Amy R. F. Bond Darryl N. Jones

Wildlife warning signs are the most commonly used and widespread form of road impact mitigation, aimed at reducing the incidence of wildlife-vehicle collisions. Evidence of the effectiveness of currently used signs is rare and often indicates minimal change in driver behaviour. Improving the design of these signs to increase the likelihood of appropriate driver response has the potential to red...

Nowadays, magnetic gears (MGs) have become an alternative choice for mechanical gears because of their low maintenance, improved durability, indirect contact between inner and outer rotors, no lubrication, and high efficiency. Generally, although these advantages, MGs suffer from inherent issues, mainly the cogging torque. Therefore, cogging torque mitigation has become an active research area....

Journal: :Microelectronics Reliability 2014
Antonio Calomarde Esteve Amat Francesc Moll Julio Vigara Antonio Rubio

In the near future of high component density and low-power technologies, soft errors occurring not only in memory systems and latches but also in the combinational parts of logic circuits will seriously affect the reliable operation of integrated circuits. This paper presents a novel design style which reduces the impact of radiation-induced single event transients (SET) on logic circuits, and ...

Journal: :International journal of radiation oncology, biology, physics 2010
Laura A Dawson Brian D Kavanagh Arnold C Paulino Shiva K Das Moyed Miften X Allen Li Charlie Pan Randall K Ten Haken Timothy E Schultheiss

The kidneys are the dose-limiting organs for radiotherapy to upper abdominal cancers and during total body irradiation. The incidence of radiotherapy-associated kidney injury is likely underreported owing to its long latency and because the toxicity is often attributed to more common causes of kidney injury. The pathophysiology of radiation injury is poorly understood. Its presentation can be a...

Journal: :Biomedical optics express 2015
Joanne Li Andrew J Bower Vladimir Vainstein Zoya Gluzman-Poltorak Eric J Chaney Marina Marjanovic Lena A Basile Stephen A Boppart

Interleukin-12 (IL-12) is a pro-inflammatory cytokine known for its role in immunity, and previous studies have shown that IL-12 provides mitigation of radiation injury. In this study, we utilize a multimodal microscopy system equipped with second harmonic generation (SHG) and fluorescence lifetime imaging microscopy (FLIM) to examine the effect of IL-12 on collagen structure and cellular metab...

Journal: :Radiation protection dosimetry 2010
Louise Lemyre Wayne Corneil Colleen Johnson Paul Boutette

Children are identified as a vulnerable population in the case of radiological events because of their increased physical sensitivity to radiation and its impact on critical development stages. Using a comprehensive integrated risk framework, psychosocial risk protective factors are discussed in a social ecology paradigm. Children have been shown to be both vulnerable and resilient; they are bo...

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