An increasing body of evidence unequivocally points to a strict inter-link between nutrition and reproduction. The paradigmatic case of leptin is examined to uncover nutritional-related physiological, cellular and molecular mechanisms. The presence of leptin receptors (Ob-R) in the ovary, oviduct, hypothalamus and anterior pituitary suggests that leptin is involved in a large array of regulator...

BACKGROUND It is known that in vivo human prion protein (PrP) have the tendency to form fibril deposits and are associated with infectious fatal prion diseases, while the rabbit PrP does not readily form fibrils and is unlikely to cause prion diseases. Although we have previously demonstrated that amyloid fibrils formed by the rabbit PrP and the human PrP have different secondary structures and...

Rabbit farming is a powerful source of dietary meat, rabbit fluff, and skins. The research was conducted at the farm Precarpathian State Agricultural Research Station Institute Agriculture Carpathian Region National Academy Agrarian Sciences. article describes creation new highly productive genetic populations rabbits identified as best options for crossing maternal paternal forms. Three breeds...

Antibody capable of sensitizing rabbit skin for passive cutaneous anaphylaxis is produced in the rabbit as early as 6 to 7 days following antigenic stimulation. It reaches peak activity around the 9th day and is gone by the 3rd wk. The antibody is heat labile, sensitive to treatment with mercaptoethanol, non-precipitating and does not fix complement. In order to demonstrate PCA activity a laten...

Ione Fine is a Professor of Psychology at the University of Washington in Seattle, USA. She studied Experimental Psychology and Philosophy at Oxford, and did her PhD with Robert Jacobs at Rochester, NY. She then fell in love with a Californian, so she moved to the University of California, San Diego to do a post-doc with Donald MacLeod and Karen Dobkins. After a brief spell at Second Sight Medi...

background and aims: methotrexate (mtx), a folic acid antagonist, is widely used as a treatment for malignancies as well as in the treatment of various inflammatory and autoimmune disorders. nephrotoxicity is an important side-effect of this drug. prevention and treatment of mtx-induced renal dysfunction are essential to prevent potentially life-threatening mtx-associated toxicities, present st...

surgical wound infections are usually encountered due to the endogenous rather than the exogenousinfective sources. the objective of this study was to evaluate the effect of a distant inoculated infective source on the contamination of surgical wounds. thirty white new zealand rabbits divided randomly into three control and three treatment equal groups. in treatment groups 24 hrs before surgica...