Quinoxaline 1,4-dioxide (4) is the historical prototype for modern heterocyclic N-oxide antitumor agents such as 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine, 1) and 3-amino-2-quinoxalinecarbonitrile 1,4-dioxide (11). Early experiments in bacterial cell lines suggested that enzymatic, single-electron reduction of quinoxaline 1,4-dioxides under low-oxygen (hypoxic) conditions leads to D...

A new Z' = 1 crystal structure of quinoxaline (or 1,4-diaza-naphthalene), C(8)H(6)N(2), with one-fifth the volume of the earlier known Z' = 5 structure was obtained by means of an in situ cryocrystallization technique.

We evaluated the effects of 23 insecticides and 9 fungicides on mite Neoseiulus barkeri（Hughes）collected from melon gerbera greenhouses. The nitenpyram, acetamiprid, flufenoxuron, chlorantraniliprole, pyridalyl, acequinocyl, cyenopyrafen, cyflumetofen, pyflubumide, fungicide flutianil＋mepanipyrim had no effect survival fecundity adult females. In contrast, spinosad, spinetoram, abamectin, emame...