In DESTINY-Breast02 (NCT03523585), T-DXd improved progression-free and overall survival vs TPC in pts with HER2+ mBC who were resistant/refractory to trastuzumab emtansine (T-DM1) (Krop et al. SABCS 2022). Here, we report data on PROs health-related quality of life (QoL). Pts (immunohistochemistry [IHC] 3+ or IHC 2+/in situ hybridization amplified) T-DM1–resistant/refractory assigned 2:1 (trast...

Introduction The addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery (CRS) improves recurrence-free (RFS) and overall survival (OS) in patients with FIGO stage III ovarian cancer. We evaluated the effect HIPEC on patient's health-related quality life (HRQoL) OVHIPEC trial. Materials methods was a multicentre, open-label, randomized phase trial for Pat...

Fatigue is a major complaint among advanced cancer patients. Several instruments are available for measuring fatigue. The EORTC QLQ-C30 is one of the most frequently used health-related quality of life (HRQOL) instruments, and it includes a three-item fatigue subscale. Limited knowledge exists about the validity, performance and sensitivity of EORTC QLQ-C30 fatigue scale as compared with a fati...

OBJECTIVE Although recent studies have improved understanding of quality of life (QOL) outcomes of breast conserving surgery, few have used longitudinal data for more than two time points, and few have examined predictors of QOL over two years. Additionally, the longitudinal data analyses in such studies rarely apply the appropriate statistical methodology to control for censoring and inter-cor...

BDI-II: Beck Depression Inventory–II; EORTC-QLQ-C30: European Organisation for Research and Treatment of CancerQuality of Life Questionnaire-C30; GHQ-12: 12 items General Health Questionnaire; PHR: Pancreatic Head Resection; PNETs: Pancreatic Neuro Endocrine Tumors; PROs: Patient-Reported Outcomes; QLQ PAN26: Quality of Life Questionnaire-PAN26; QoL: Quality of Life; SF-12: Medical Outcome Stud...