Pustular psoriasis of pregnancy (PPP) is a life-threatening condition for both the pregnant mother and fetus, and must be efficiently and accurately diagnosed and treated. This condition has historically been classified as a unique, separate dermatosis of pregnancy. However, current opinion and data suggest that it may be a variant of generalized pustular psoriasis. PPP typically occurs in the ...

Introduction In major reviews of amyloidosis (Glenner, Terry and Isersky, 1973; Stirling, 1975) psoriasis is not listed as one of the predisposing causes nor is it mentioned as an aetiological factor in renal amyloidosis (Heptinstall, 1974). Case reports have drawn attention to amyloidosis in patients with pustular psoriasis (Berger, 1969; Mackie and Burton, 1974) and psoriatic arthritis (Reed ...

Palmoplantar pustular psoriasis (PPP) is a chronic inflammatory skin condition mainly characterized by recurrent eruptions of sterile pustules on erythematous skin; hyperkeratosis and fissures on the palms and soles are additional clinical features. Treatment options for PPP are unsatisfactory. We present a patient with a typical course of PPP that had previously received a broad range of topic...

BACKGROUND Current medical daily practice relies on guidelines, protocols and procedures (GPPs), which require exploitation. However, diagnosis, treatment, risk management and process improvements require exploration. Physician are often unable to switch between exploitation and exploration. This study tested a new approach to facilitate switching that included (1) a new 'thinking protocol' tha...

Impetigo herpetiformis (IH) is a very rare and specific pustular dermatosis of pregnancy that can be life-threatening for both mother child. This entity currently considered as variant psoriasis. We report an observation 35-year-old female patient who presented with extensive erythematous-pustular plaques which the diagnosis impetigo herpetiformiswas made clinically histologically. The lesions ...

The Gulf Journal of Dermatology and Venereology ABSTRACT Psoriasis vulgaris and bullous pemphigoid represent two clinically well-characterized, chronic, inflammatory skin diseases. The concomitant occurrence of these two entities in a patient is rare, and the exact nature of this relationship is not clear. We describe a 31-year-old woman with a history of plaque-type psoriasis who presented wit...

BACKGROUND Palmoplantar psoriasis is a difficult to treat variant of plaque psoriasis. OBJECTIVE To study the safety and efficacy of infliximab in non-pustular palmoplantar psoriasis. METHODS Patients with non-pustular palmoplantar psoriasis affecting at least 10% of their palms and soles and with a modified palmoplantar psoriasis area and severity index (m-PPPASI) of at least eight were re...

Since 1991, eight cases of pulmonary leak capilary syndrome have been described associated with pustular or erythrodermic psoriasis induced or not by the use of acitretin or sirolimus - being one of the cases, fatal. We report the case of a female patient with diagnosed GPP or von Zumbusch and multiple hospitalizations due to such condition. At that time, the condition was evolving with pulmona...

Risankizumab, a humanized immunoglobin G1 monoclonal antibody that specifically inhibits interleukin 23 by binding to its p19 subunit, is approved in Japan treat numerous indications, including generalized pustular psoriasis (GPP) and erythrodermic (EP). Both GPP EP are severe forms of have limited treatment options. In IMMspire (A Study Assess Efficacy Safety Two Different Dose Regimens Risank...