evidence of reduced venous return and alternating end-diastolic fiber length as causative factors. To the Editor: Attie et al.' reported their experience with valve replacement in children with mitral insufficiency. They divided their patients in three groups, depending on the type of prosthesis: mechanical valves, porcine xenografts and dura mater valves. Follow up times were 6.3, 3.3 and 1.9 ...

Herein, we present the case of a 10-year-old child suffering from right-sided infective endocarditis with ventricular septal defect. Echocardiography revealed multiple rare large vegetations on the pulmonary valve extending into pulmonary artery along with a large vegetation over the septal leaflet of the tricuspid valve. 

The quest for a perfect heart valve substitute has been going on for half a century. In 1960, Lower et al1 described the feasibility of replacing the aortic valve of dogs with the native pulmonary valve. In 1967, Ross performed this procedure in humans.2 Ross transferred the pulmonary valve into the aortic root with the same technique used to implant aortic valve homograft3 (ie, the pulmonary s...

brucella endocarditis is a rare, and life threatening complication of human brucellosis. children are usually infected by consumption of contaminated dairy product. clinical presentation is similar to rheumatic fever. aortic valve is most commonly involved. clinical manifestations of fever, arthritis/arthralgia, aortic insufficiency, echocardiographic evidence of vegetation, and negative findin...

Severe aortic insufficiency may accelerate mitral valve closure. We noted this echocardiographic finding in several patients with the acute onset of severe aortic insufficiency. Accordingly, we examined our total echocardiographic series retrospectively for early closure of the mitral valve (ECMV) in the setting of aortic insufficiency and found it in 11 of 53 patients with confirmed aortic ins...

Debate continues regarding the long-term clinical and hemodynamic benefit of homograft replacement of the diseased mitral valve. The results of valve replacement with mitral homografts in the 120 patients who have had operation at the Stanford Medical Center from May 1967 to November 1970 are given. The operative mortality rate has been 5% and the late mortality rate 6%. Anticoagulants were sto...

Pulmonary arterial early diastolic waves (V waves) were investigated in patients and experimental animals with mitral regurgitation. V waves exceeding systolic pressure in the pulmonary artery were recorded in the main pulmonary artery with micromanometer catheters both in patients and animals, eliminating the possibility of catheter artifact. In experimental animals, aortic closure preceded pu...

background: left ventricular (lv) twist is due to oppositely directed apical and basal rotation and has been proposed as a sensitive marker of lv function. we sought to assess the impact of chronic pure mitral regurgitation (mr) on the torsional mechanics of the left human ventricle using tissue doppler imaging. methods: nineteen severe mr patients with a normal lv ejection fraction and 16 non-...

global myocardial ischemia and ischemia-reperfusion injury are potential adverse events related with cardioplegic arrest. beating heart surgery has avoided such complications and adapted to valve surgery following successful results published on myocardial revascularization. difficulty in weaning from cardiopulmonary bypass may be lessened by using on-pump beating heart surgery for mitral valve...