This case report describes a previously healthy 55 year-old man with unremarkable family and medical history presenting with Cotard delusion, unintentional weight loss, and psychomotor agitation requiring sedation. Testing revealed CSF leukocytosis and erythrocytosis, leading to a preliminary diagnosis of viral herpes encephalitis. As the patient continued to deteriorate, anti-NMDA receptor ant...

OBJECTIVE To investigate the relationship between sedation and the memories reported by patients subjected to mechanical ventilation following discharge from the intensive care unit. METHODS This prospective, observational, cohort study was conducted with individuals subjected to mechanical ventilation who remained in the intensive care unit for more than 24 hours. Clinical statistics and sed...

Objective: To investigate the association between aggression in the first 24 hours after admission and severity of psychopathology in psychiatric inpatients. Methods: This cross-sectional study included psychiatric patients admitted to Hospital Universitário de Santa Maria, in Santa Maria, southern Brazil, from August 2012 to January 2013. At their arrival at the hospital, patients were intervi...

Primary intracranial melanomas are rare, with a challenging diagnosis based only on clinical and imaging features. The authors described the case of an intracerebral right parieto-temporal melanoma mimicking cavernoma in patient affected by Crohn’s disease. A 67-year-old female disease small bowel stenosis was hospitalized for surgical removal terminal ileum latero-lateral ileo-colic anastomosi...

The patient was a single, 36year-old white man. He was admitted to our institution due to agitated behavior and psychosis, with a diagnosis of bipolar I disorder from his most recent episode, which was mixed and severe with moodincongruent psychotic features. He presented with depressed mood of 3 weeks’ duration, associated with early and intermittent insomnia, decreased energy, racing thoughts...

Controlled studies of tranquillizers, both phenothiazine and rauwolfia derivatives, show improvement in those patients staying for long periods in hospital in such symptoms as motor restlessness, psychomotor agitation and excitement (Vaughan, Leiberman, and Cook, 1955), tension, delusions, hostility, and sociability (Wing, 1956). Few authors discuss the outcome in terms of the patients' dischar...

Both normal aging and dementia are associated with altered circadian regulation of physiology and behavior. Elderly individuals and dementia patients commonly experience disrupted sleep-wake cycles, which may lead to psychomotor agitation, confusion, and wandering. These behaviors are disruptive to both patients and caregivers. Sundowning syndrome, which encompasses many of these behaviors, is ...

Acute confusional migraine (ACM) is recognized as a rare, but highly disabling migraine equivalent, mostly reported in children and adolescents. Herein we describe the case of a 12-year-old girl admitted to hospital for an acute confusional state and severe psychomotor agitation, associated with a pulsating headache and nausea, which turned out to be a manifestation of ACM. The girl was dischar...

We describe herein an unusual case of subacute thyroiditis presenting as acute psychosis. An 18-year-old male presented at the emergency department due to abnormal behavior, psychomotor agitation, sexual hyperactivity, and a paranoid mental state. Laboratory findings included an erythrocyte sedimentation rate of 36 mm/hr (normal range, 0 to 9), free T4 of 100.0 pmol/L (normal range, 11.5 to 22....

OBJECTIVE OF THE STUDY to analyze the efficiency and safety of Dexmedetomidine infusion for a short-term controlled sedation and treatment of delirium in the early postoperative period in patients after cardiac surgery. METHODS open, randomized, prospective study of 28 patients undergoing surgery on the heart or main blood vessels under general anaesthesia. In the early postoperative period a...