Extracellular transients of pH alterations likely mediate signal transduction in the nervous system. Neuronal acid-sensing ion channels (ASICs) act as sensors for extracellular protons, but the mechanism underlying ASIC activation remains largely unknown. Here, we show that, following activation of a light-activated proton pump, Archaerhodopsin-3 (Arch), proton transients induced ASIC currents ...

Enzymes of the mitochondrial respiratory chain serve as proton pumps, using the energy made available from electron transfer reactions to transport protons across the inner mitochondrial membrane and create an electrochemical gradient used for the production of ATP. The ATP synthase enzyme is reversible and can also serve as a proton pump by coupling ATP hydrolysis to proton translocation. Each...

The general equation governing the mass, spin and angular momentum of a KerrNewman black hole applies equally well to a proton when the gravitational coupling constant predicted by a discrete fractal paradigm is used in the equation, along with the standard mass, spin and angular momentum of the proton. c © Electronic Journal of Theoretical Physics. All rights reserved.

We present two models for electron-driven uphill proton transport across lipid membranes, with the electron energy converted to the proton gradient via the electrostatic interaction. In the first model, associated with the cytochrome c oxidase complex in the inner mitochondria membranes, the electrostatic coupling to the site occupied by an electron lowers the energy level of the proton-binding...

The reaction pp → ppφ is investigated within a relativistic mesonexchange model of hadronic interactions. The possibility of extracting the NNφ coupling constant from a study of this process is explored. A combined analysis of ω− and φ-meson production in proton-proton collisions utilizing recent data on these reactions is carried out and yields values for gNNφ that are compatible with the OZI ...

PURPOSE The objective of this study was to determine whether a sodium phased array would improve sodium breast MRI at 3 T. The secondary objective was to create acceptable proton images with the sodium phased array in place. METHODS A novel composite array for combined proton/sodium 3 T breast MRI is compared with a coil with a single proton and sodium channel. The composite array consists of...

The 1H and 15N NMR spectra of several 15N-labeled pyridoxal-5'-phosphate model systems have been measured at low temperature in various aprotic and protic solvents of different polarity, i.e., dichloromethane-d2, acetonitrile-d3, tetrahydrofuran-d8, freon mixture CDF3/CDClF2, and methanol. In particular, the 15N-labeled 5'-triisopropyl-silyl ether of N-(pyridoxylidene)-tolylamine (1a), N-(pyrid...

A comparative theoretical investigation of single electron transfer (ET), single proton transfer (PT), and proton-coupled electron transfer (PCET) reactions in iron bi-imidazoline complexes is presented. These calculations are motivated by experimental studies showing that the rates of ET and PCET are similar and are both slower than the rate of PT for these systems (Roth, J. P.; Lovel, S.; May...

The characteristics of the thermal radiation are investigated using a two-component model, with hard component being described by Color Glass Condensate formalism. inclusive transverse momentum spectra charged hadrons produced in proton–proton and proton–nucleus collisions at LHC energies large - $$p_T$$ estimated running coupling $$k_T$$ -factorization formula solution Balitsky–Kovchegov equat...