The neutral form of the chromophore in wild-type green fluorescent protein (wtGFP) undergoes excited-state proton transfer (ESPT) upon excitation, resulting in characteristic green (508 nm) fluorescence. This ESPT reaction involves a proton relay from the phenol hydroxyl of the chromophore to the ionized side chain of E222, and results in formation of the anionic chromophore in a protein enviro...

Amino acid radical generation and transport are fundamentally important to numerous essential biological processes to which small molecule models lend valuable mechanistic insights. Pyridyl-amino acid-methyl esters are appended to a rhenium(I) tricarbonyl 1,10-phenanthroline core to yield rhenium-amino acid complexes with tyrosine ([Re]-Y-OH) and phenylalanine ([Re]-F). The emission from the [R...

Recently, the chemistry of element (0) compounds has attracted the attention of both experimental and theoretical chemists. In this article, some new Si(0) and Ge(0) compounds stabilized by different silylene and germylene ligands are studied theoretically by applying quantum chemical calculations and topography mapping of molecular electrostatic potential (MESP). These compounds are found to h...

Using density functional theory we look at the quantum mechanics of charge transport along water wires both with free ends and donor/acceptor terminated. With the intermediate geometries in the DFT iterations we can follow the charge transfer mechanism and also construct the energy landscape explicitly. It shows activation barriers when a proton is transferred from one water molecule to the nex...

A glutamide gelator, 1, was synthesized, and a weak emission enhancement was observed during its gelation. In addition, 1 could be an excellent scaffold for successfully embedding an energy acceptor, 2, into its aggregate to obtain highly efficient energy transfer. An amplification of the emission enhancement was observed in the two-component gels compared to that of the neat gel of 1 during ge...

Diaminopimelic acid epimerase was purified from Escherichia coli. The enzyme is a monomer of Mr = 34,000. Diaminopimelic acid epimerase is not a pyridoxal phosphate-dependent enzyme: there is no evidence for pyridoxal phosphate in the ultraviolet spectrum of the purified enzyme, and the epimerase is not inactivated by carbonyl reagents such as hydroxylamine and sodium borohydride. Exchange of t...

The title compound, 2C(4)H(12)N(2) (2+)·C(10)H(2)O(8) (4-)·6H(2)O or (pipzH(2))(2)(btc)·6H(2)O, was formed from the reaction between benzene-1,2,4,5-tetra-carboxylic acid (btcH(4)) as a proton donor and piperazine (pipz) as a proton acceptor. A variety of O-H⋯O, N-H⋯O and C-H⋯O hydrogen bonds, as well as C-H⋯π inter-actions, are present in the crystal structure. Two water O atoms are each disor...