It has been reported (1) that cystine is metabolized by resting cells of Proteus vulgaris and Proteus morganii to pyruvate, ammonia, and hydrogen sulfide, Toluene-killed cells of P. morganii also carried out the reaction and to a lesser degree attacked homocysteine, yielding hydrogen sulfide, ammonia, and some unidentified product. Inasmuch as the use of toluene-killed cells may not obviate ent...

Fifteen beta-lactam antibiotics were divided into four classes based on their antibacterial actions and beta-lactamase-inducing activities in Proteus vulgaris. One of these groups, which included cefmenoxime, ceftriaxone, cefuzonam, and cefotaxime, showed a clear paradoxical antibacterial activity against P. vulgaris. This group showed growth-inhibitory activity at relatively low concentrations...

Two novel sequence-specific endonucleases have been isolated from Proteus vulgaris, ATCC 13315. PvuI recognizes the sequence: 5' C G A T decrease C G 3' 3' G C increase T A G C 5' and PvuII recognizes the sequence: 5' C A G decrease C T G 3' 3' G T C increase G A C 5' and cleave as indicated by the arrow (decrease). PvuI is an isoschizomer of XorII, RshI, and XniI. No enzyme with the specificit...

In this study we deal with the cultural properties, the products of growth, the pathogenicity, and the toxicity, of two strains of Proteus vulgaris, Hauser. This is an exceedingly interesting organism on account of its wide distribution, the ease with which it is modified, and because it seems to stand between the true saprophytic and the purely pathogenic bacteria. It has been found under a gr...

In Bacillus subtilis the reduction of potassium tellurite and of tetranitro-blue tetrazolium (TNBT) give comparable results: reduced products appear deposited in particular membranous organelles. For this reason these specialized organelles are considered to be chondrioids (1-3). In the Gram-negative Proteus vulgaris similar membranous structures were never observed by us (4, 5). Therefore it i...

Antibaterial activity against Escherichia coli, proteus vulgaris, pseudomonas aeruginosa and staphylococcus aureus was tested for the petroleum ether (60-80°C) chloroform and aqueous leaf extract of strobilanthus kunthiana by disc diffusion method. Profound antibacterial activity was observed for all the leaf extract.

A study was undertaken on the presence and frequency of Listeria sp. in feces from 1,000 patients suffering from diarrheal diseases and from 2,000 healthy persons. Furthermore, the feces of patients were examined for other well-documented enteropathogens such as Campylobacter, Salmonella, Shigella, Staphylococcus aureus, Yersinia enterocolitica, protozoa and rotavirus as well as for organisms o...

A range of silver-coated or -impregnated dressings are now commercially available for use but comparative data on their antimicrobial efficacies are limited. The antibacterial activities of five commercially available silver-coated/impregnated dressings were compared against nine common burn-wound pathogens, namely methicillin-sensitive and -resistant Staphylococcus aureus (MRSA), Enterococcus ...

Duguid (1946) suggested, as a result of observations on bacteria treated with penicillin, that this antibiotic might inhibit the formation of the outer supporting cell wall. Bonifas (1954) observed the formation of globular bodies when cultures of Proteus vulgaris were treated with penicillin, and investigated the effect of hypertonic media, already used to stabilize the lysozyme induced protop...

The antimicrobial activity of flumequine (R-802) was characterized by in vitro and in vivo procedures. Assay of the minimal inhibitory concentrations for 321 recent clinical isolates revealed that 88% of the gram-negative bacteria were inhibited by an R-802 concentration of 6.2 mug/ml or less. Cross-resistance in laboratory-derived mutants of Proteus vulgaris was essentially complete for R-802,...