One of the most pressing problems of the post genomic era is identifying protein functions. Clustering Protein-Protein-Interaction networks is a systems biological approach to this problem. Traditional Graph Clustering Methods are crisp, and allow only membership of each node in at most one cluster. However, most real world networks contain overlapping clusters. Recently the need for scalable, ...

UNLABELLED Cellular processes are regulated by interaction of various proteins i.e. multiprotein complexes and absences of these interactions are often the cause of disorder or disease. Such type of protein interactions are of great interest for drug designing. In host-parasite diseases like Tuberculosis, non-homologous proteins as drug target are first preference. Most potent drug target can b...

objective: despite the huge efforts, chronic kidney disease (ckd) remains as an unsolved problem in medicine. many studies have shown a central role for transforming growth factor beta-1 (tgfβ-1) and its downstream signaling cascades in the pathogenesis of ckd. in this study, we have reanalyzed a microarray dataset to recognize critical signaling pathways controlled by tgfβ-1. materials and met...