نتایج جستجو برای: protein interaction network could reveal

تعداد نتایج: 3036235  

Journal: :Molecular cell 2012
Anna Hegele Atanas Kamburov Arndt Grossmann Chrysovalantis Sourlis Sylvia Wowro Mareike Weimann Cindy L Will Vlad Pena Reinhard Lührmann Ulrich Stelzl

More than 200 proteins copurify with spliceosomes, the compositionally dynamic RNPs catalyzing pre-mRNA splicing. To better understand protein - protein interactions governing splicing, we systematically investigated interactions between human spliceosomal proteins. A comprehensive Y2H interaction matrix screen generated a protein interaction map comprising 632 interactions between 196 proteins...

2008
Yong Wang Yu Xia

Subnetworks can reveal the complex patterns of the whole-genome network by extracting the interactions that depend on temporal, spatial, or condition specific context. In this paper we present an optimization framework to identify condition specific subnetworks. This framework allows us to identify the most coherent subnetwork by integrating the information from both nodes and edges in the grap...

Journal: :iranian journal of biotechnology 2013
changiz eslahchi

background: protein-protein interactions do not provide any direct information re­garding the domains within the proteins that mediate the interactions. the majority of proteins are multi domain proteins and the interaction between them is often defined by the pairs of their domains. most of the former studies focus only on interacting do­main pairs. however they do not consider the interaction...

Journal: :Proceedings of the National Academy of Sciences 2003

Journal: :Frontiers in Systems Neuroscience 2009

Journal: :CPT: Pharmacometrics & Systems Pharmacology 2015

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