The correlation between both prostate specific antigen levels (PSA) and prostate specific antigen density (PSAD) and age, prostate volume parameters, body mass index, and the International Prostate Symptom Score (IPSS) were studied in a community-based population. A sample of 502 men aged 55 through 74 years was evaluated, excluding those with a serum PSA above 10 ng/ml, those with biopsy prove...

The article demonstrates that prostate-specific antigen (PSA) has some limitations in detection of cancer of prostate. It was demonstrated that isoform of free PSA - 2proPSA has higher specificity in comparison with total PSA (tPSA) and percentage tPSA and free PSA (%free PSA) in detection of cancer of prostate. The application of Prostate Health Index including such indicators as -2PSA, free P...

Background Testing for prostate-specific antigen (PSA) is often recommended men with a potential risk of prostate cancer (PCa) before requiring advanced examination. However, the best PSA cutoff value remains controversial. Object We compared predictive performance age-specific percentile-based thresholds conventional >4 ng/mL PCa. Methods included who received measurements between 2003 and 201...

background: the serum prostate specific antigen (psa) levels are used for prostate cancer screening. some conditions such as prostatitis, manipulation, and prostate cancer could influence on serum psa. the impact of ejaculation on serum psa is controversial. the aim of our study was to evaluate the relation of ejaculation and the levels of serum psa. materials and methods: in this cross-section...

Prostate cancer is the most common neoplasia of middle-aged men. Prostate specific antigen (PSA) is the first FDA-approved tumour marker for early detection of cancer and it is now in widespread clinical use. The discovery of different PSA molecular forms in serum (free PSA, PSA complexed with various protease inhibitors) in the early 1990s renewed clinical research to enhance the specificity o...

Objective(s): Prostate cancer (PC) is the most common cancer in men over 50 years of age. Bone scintigraphy is still performed in many institutions at the time of primary diagnosis. We aimed to evaluate the role of bone scan in the primary staging of PC in regard of different risk groups. Methods: A retrospective analysis of bone scans i...

This article presents a rare case of a common disease, prostate cancer. A 57 year-old patient undergoing annual check-up for prostate cancer presents with a prostate specific antigen (PSA) level as low as 0.64 ng/ml. This patient was revealed to suffer from prostate cancer pT2c pNx pMx. This article assesses the implications of low prostate specific antigen for prostate cancer and discusses the...

Purpose: Benign Prostatic Hyperplasia (BPH) is an important cause of morbidity for ageing men worldwide. However, the available study limited on natural history BPH and dynamics Prostate-Specific Antigen (PSA) in Sri Lankan population. This aimed to assess relationship between serums Prostate Specific (PSA), prostate volume (PV), PSA density (PSAD) evaluate variations above parameters with agin...

Total serum prostate-specific antigen (PSA) levels, free-to-total PSA ratio (F/T ratio) and PSA density (PSAD) were compared to clarify the clinical significance of these parameters in the diagnosis of prostate cancer (CaP) with intermediate PSA concentrations (4-10 ng/ml). PSAD and F/T ratio were obtained during the period from May 1999 to April 2001 from 43 patients with serum PSA concentrati...