Email: [email protected] Abstract Background: A transrectal ultrasound-guided prostate biopsy is currently the gold standard procedure to detect prostatic adenocarcinoma. There is little information on the clinical utility of this technique for the detection of prostate adenocarcinoma in men with suspected prostate cancer in Pakistan. This study seeks to determine the frequency of prostat...

Prostate cancer is one of the most common cancers among men worldwide and in the USA. Most prostate cancer progression either locally invades to seminal vesicles or metastasizes distally to bone. Skin is not a common site of metastasis for the majority of malignancies including prostate cancer. This paper reports two extremely rare cases of prostate carcinoma metastatic to the skin: a 74-year-o...

INTRODUCTION To investigate the clinical features, diagnosis, treatment, and prognosis of ductal adenocarcinoma of the prostate. METHODS The clinicopathological and immunohistochemical data of seven patients with ductal adenocarcinoma of the prostate were retrospectively analyzed. All patients underwent physical examination, magnetic resonance imaging (MRI), bone scan, cystoscopy, and compute...

Prostatic small cell carcinoma is an aggressive subtype of prostate cancer that usually appears as a progression of the original adenocarcinoma. We describe here the WISH-PC2, a novel neuroendocrine xenograft of small cell carcinoma of the prostate. This xenograft was established from a poorly differentiated prostate adenocarcinoma and is serially transplanted in immune-compromised mice where i...

Introduction: Prostate cancer is the second common malignancy in men. Prostatic intraepithelial neoplasia (PIN) precursor lesion of prostatic carcinoma. Histopathological examination necessary to diagnose PIN lesions. Objective: The aim study determine incidence and analyse usefulness basal cell marker p63 expression various lesions prostate. Methods: This a two-year prospective 65 transurethra...

Prostate cancer is the most common cancer in men, excluding skin cancer. Globally, it is the sixth leading cause of cancer-related death in men, and the second one in the United States 1. Rates of prostate cancer detection vary widely across the world, but the highest rates occur in the developed countries. Since the introduction of the prostate-specific antigen (PSA) as screening method, the e...

A 64-year-old man with a prostate-specific antigen (PSA) of 5·74 ng/mL, no lower urinary symptoms, and family history prostate cancer presented at our clinic University College London Hospital (London, UK) in April, 2018. Axial T2-weighted MRI the showed multicystic lesion (PSA density 0·07 ng/mL/mL), MRI-targeted biopsies Gleason 3 + adenocarcinoma (Gleason Grade Group 1) prostatic intraepithe...

Small cell carcinoma (SCC) of the prostate is a rare and recently recognized subtype of prostate cancer. The neuroendocrine component of the prostate carcinoma is becoming more frequently detected in classic adenocarcinoma of the prostate. Clinically, these tumors represent a considerable portion of so called androgen independent prostatic carcinomas. It has been hypothesized that the neuroendo...

A 74-year-old man initially presenting with fall had an incidental finding on CT of a heterogeneous, partly cystic lesion in the pelvis that was moderately glucose avid FDG-PET. The pelvic mass and adherent right seminal vesicle were excised. On microscopy, comprised benign prostatic acini supported by fibromuscular stroma to normal vesicle. tissue stained positive for NKX3.1 PSMA. PIN4 showed ...

Although adenocarcinoma of the prostate persists in being the most common form of cancer in men, its clinical behavior does not maintain this type of consistency, wavering from extremely aggressive fatal cancers to clinically insignificant, incidental entities. The prevalence of prostate cancer at autopsy is remarkably high, increasing from 20% in men in their 50s to up to 80% in men 70 to 80 y...