An extensive review of the spinal and arthroplasty literature was undertaken to evaluate the effectiveness of local antibiotic irrigation during surgery. The efficacy of antibiotic irrigation for the prevention of acute post-operative infection after total joint arthroplasty was evaluated retrospectively in 2293 arthroplasties (1990 patients) between January 2004 and December 2013. The mean fol...

OBJECTIVE Clinical studies of patients with bone sarcomas have been challenged by insufficient numbers at individual centres to draw valid conclusions. Our objective was to assess the feasibility of conducting a definitive multi-centre randomised controlled trial (RCT) to determine whether a five-day regimen of post-operative antibiotics, in comparison to a 24-hour regimen, decreases surgical s...

Infections are second leading cause of mortality preceded only by cardiovascular diseases.1 Neonates in particular are at a high-risk of developing bloodstream infections because of their immature immune system and mucosal surfaces.2,3 In neonates, sepsis has repeatedly been indicated to be an important cause of mortality, with preterm and very low birth weight (<1500g) infants being at the hig...

VOL. 75-B. No. JANUARY 1993 from a tarsometatarsal (Lisfranc)dislocation is important (Faciszewski, Burks and Manaster 1990). Our patient presented at three weeks and conservative treatment enabled her to return to athletics without symptoms seven months after the injury. O’Donoghue (1976) recommended complete reduction and internal fixation followed by non-weight-bearing for four weeks and an ...

OBJECTIVE Inhalation injury is suspected in patients with facial and neck burn-injuries and in patients who suffered burns in an enclosed space. Inhalation injury is associated with a disappointingly high morbidity and mortality in spite of advances in diagnostics and therapy.Prophylactic antibiotic therapy in patients with diagnosed inhalation injury is still a controversial subject.The epidem...

OBJECTIVES To assess the use of prophylactic antibiotics for cesarean section, and to identify factors associated with a doctor's intraoperative prescription. DESIGN A hospital-based, cross-sectional study. STUDY PARTICIPANTS All 967 medical records of women undergoing cesarean section from January 1998 to February 1999 in a university hospital, Southern Thailand. MAIN MEASURES Independen...

According to the authors, prophylactic antibiotics should not be used routinely in aesthetic surgery, but only when indicated by empirically-based criteria. Here they provide literature-based guidelines, advocate for new double-blinded studies, and advise aesthetic surgeons to decide on prophylactic antibiotic treatment by considering the relative risks and benefits in each individual case.

(Chest 1990; 98:719-23) U se of peniolperative antibiotics for cardiothoracic surgical procedures has been established for many I However, the actual use of these agents in everyday practice is not known. The Steering Committee of the Section of Cardiothoracic Surgery sunveyed the surgical membership of the American College of Chest Physicians to determine the actual use (If prophylactic agents...

BACKGROUND Surgeons operating in the head and neck commonly treat facial fractures; however, the role of prophylactic antibiotics remains controversial. Facial fractures vary in location and severity and can span the range of wound classifications including clean, clean contaminated, contaminated, and dirty/infected. It is clear that actively infected facial fractures should be treated with the...