proliferator

related receptor α directs peroxisome proliferator-activated receptor α signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle.

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Ligands of peroxisome proliferator-activated receptor- increase the generation of vascular endothelial growth factor in vascular smooth muscle cells and in macrophages

2000

Alicja Jozkowicz Jozef Dulak Ewa Piatkowska Wojciech Placha Aldona Dembinska-Kiec

Peroxisome proliferator-activated receptors-g (PPARg) are ligand-inducible transcription factors of the nuclear hormone receptor superfamily. We examined the ef

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Nanoparticle-mediated delivery of pioglitazone enhances therapeutic neovascularization in a murine model of hindlimb ischemia.

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2012

Ryoji Nagahama Tetsuya Matoba Kaku Nakano Shokei Kim-Mitsuyama Kenji Sunagawa Kensuke Egashira

OBJECTIVE Critical limb ischemia is a severe form of peripheral artery disease (PAD) for which neither surgical revascularization nor endovascular therapy nor current medicinal therapy has sufficient therapeutic effects. Peroxisome proliferator activated receptor-γ agonists present angiogenic activity in vitro; however, systemic administration of peroxisome proliferator-activated receptor-γ ago...

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