Background: The goal of antivenom administration for snake-bitten patients is to achieve therapeutic response (initial control), which means reversal of the venom-induced effects through neutralizing the venom. The aim of this study was to identify snakebite prognostic factors of weak therapeutic response prior to antivenom administration. Methods: This was a retrospective study of patients wit...

BACKGROUND Prognostic nutritional index has been shown to be a prognostic marker for various solid tumors. However, few studies have investigated the impact of the prognostic nutritional index on survival of patients with breast cancer. The aim of this study was to investigate the impact of the prognostic nutritional index on the long-term outcomes in patients with breast cancer. METHODS This...

BACKGROUND Prognosis is a key driver of clinical decision-making. However, available prognostication tools have limited accuracy and variable levels of validation. METHODS Principles of survival prediction and literature on clinician prediction of survival, prognostic factors, and prognostic models were reviewed, with a focus on patients with advanced cancer and a survival rate of a few month...

abstract objectives: tumour necrosis factor α (tnfα) and lymphotoxin α (ltα) have been implicated in the pathogenesis of lymphoproliferative disorders. patients with b-cell non-hodgkin’s lymphoma (nhl) often have high serum levels of tnf which may be associated with a poor outcome. tnfα and ltα polymorphisms are known to influence expression of these cytokines and may explain the variable respo...

background: cerebral venous-sinus thrombosis is an uncommon form but important cause of stroke, especially in young-aged women. methods: we performed a retrospective descriptive-analytical study in which 124 patients with cerebral venous-sinus thrombosis, who referred to nemazee hospital, shiraz university of medical sciences from january 2000 to march 2008, were included, and their demographic...

background: gastric and colorectal adenocarcinoma are the second and the fifth most common cancers in iran, respectively. expression of cytokeratin 7 (ck7) is established in most malignancies including gastric and colorectal adenocarcinoma. demonstration of ck7 could be related to prognostic factors and help to the better management of the patients. the objective of our study was to evaluate th...

background: focal segmental glomerulosclerosis (fsgs) is a type of nephrotic syndrome which is diagnosed by renal biopsy. degree of the proteinuria, renal dysfunction, histologic findings and the response to therapy are some factors used for evaluating the prognosis of fsgs. objectives: in the present study, we attempted to discover some protein candidates for disease prognosis related to glome...

OBJECTIVES Immunological parameters and nutritional status influence the outcome of patients with malignant tumors. A prognostic nutritional index, calculated using serum albumin levels and peripheral lymphocyte count, has been used to assess prognosis for various cancers. This study aimed to investigate whether this prognostic nutritional index affects overall survival and the incidence of pos...