Process monitoring and fault diagnosis using profile data remains an important and challenging problem in statistical process control (SPC). Although the analysis of profile data has been extensively studied in the SPC literature, the challenges associated with monitoring and diagnosis of multichannel (multiple) nonlinear profiles are yet to be addressed. Motivated by an application in multi-op...

We present some practical extensions and applications of a strategy proposed by Thall, Simon and Estey for designing and monitoring single-arm clinical trials with multiple outcomes. We show by application how the strategy may be applied to construct designs for phase IIA activity trials and phase II equivalence trials. We also show how it may be extended to incorporate the use of mixture prior...

The global power sector is facing a number of issues, but the most fundamental challenge is meeting the rapidly growing demand for energy services in a sustainable way. This challenge is further compounded by the today’s volatile market rising fuel costs, increased environmental regulations, etc. Plant owners are challenged to prepare for the impact of future fuel price increases and carbon tax...

BACKGROUND Clinical research and drug development in orphan diseases are challenging, since large-scale randomized studies are difficult to conduct. Formally synthesizing the evidence is therefore of great value, yet this is rarely done in the drug-approval process. Phase III designs that make better use of phase II data can facilitate drug development in orphan diseases. METHODS A Bayesian m...

Statistical process control (SPC) is widely used in industrial settings to monitor processes for shifts in their distributions. SPC is generally thought of in two distinct phases: Phase–I, in which historical data is analyzed in order to establish an in–control process, and Phase–II, in which new data is monitored for deviations from the in–control form. Traditionally, SPC had been used to moni...

mobile carrier properties of two schiff base ligands, named bis(2-hydroxypropiophenone)-1,2-propanediimine (n2o2) and bis(1'-hydroxy-2'-acetonaphthone)-2,2'-diiminodiethylamine (n3o2), dissolved in dichloromethane for the extraction of copper(ii) ions from an ammonium buffer feed phase into a nitric acid solution (receiving phase) were investigated and compared. the parameters influencing the t...

Electrochemical impedance spectroscopy (EIS) was used to detect stress corrosion cracking (SCC) in stainless steel 304 alloy exposed to an aqueous environment at 120 °C. Stainless steel 304 alloy as u-bend was tested in the solution that contains 40 weight percent of magnesium chloride. U-bended samples were prepared according to ASTM G30. EIS measurements were always performed simultaneously o...