نتایج جستجو برای: pro

تعداد نتایج: 83908  

Maryam Rouintan Mohammad Ali Mousavi

Abstract The feminist movement in the United States like other countries has tried to establish equality for women. From the first attempts to gain constitutional right for vote, up to the current radical demands, feminists have struggled to make changes in the U.S. party politics and obtain their rights within the parties. One of the important issues in which women played a key role in party ...

امیری, پروین , اکرمی, سید محمد , حشمت, رامین , دوستی, محمود , میرزایی, حسن , نخجوانی, منوچهر , گل محمدی, تقی ,

Background: Peroxisome Proliferators- Activated Receptor-Gamma2 (PPAR- γ2) is a nuclear receptor that regulates adipocyte differentiation, lipid metabolism and insulin sensitivity. The aim of this study was to evaluate the association of the Pro12Ala polymorphism at the PPAR- γ2 gene in Iranian population with obesity. Methods: The genomic DNAs of the 156 subjects including obese and healthy i...

بهادری , محمد هادی, فغانی , معصومه, نصیری , ابراهیم, محمد قاسمی , فهیمه ,

چکیده مقدمه: سرطان پستان شایع‌ترین سرطان در زنان جهان است. ژن سرکوب کننده تومور 53P نقش مهمی در پایداری ژنومی دارد و عملکرد این پروتیین 53P به‌دنبال پلی مورفیسم کدون 72 تغییر می‌کند. هدف: بررسی پلی مورفیسم ژن 53P و تاثیر یائسگی در ایجاد کارسینومای مجرایی مهاجم پستان مواد و روش‌ها: برای تعیین پلی مورفیسم کدون 72، 96 نمونه سرطانی از نوع کارسینومای مجرایی مهاجم و 96 نمونه کنترل در شهر اصفه...

Background: Acute respiratory distress (ARD) is a critical respiratory failure due to lung injury of neonates leading to the clinical appearance of poor lung compliance. The aimed of the study was to evaluate the diagnostic values in differentiating respiratory from heart diseases with using of N-terminal pro brain natriuretic peptide (NT-pro BNP) and Atrial natriuretic peptide(ANP) in neonates...

Journal: :گوارش 0
masoumeh faghani saba fakhrieh

background : colorectal cancer is the second cause of mortality in developed countries. the p53gene and some of it's polymorphisms are among the causes for cancer development.the purpose of this study is to evaluate the relationship between the p53 codon 72 polymorphism in colorectal adenocarcinoma specimens compared with controls. materials and methods : we performed a case-control study among...

ژورنال: :مجله دانشکده پزشکی اصفهان 0
معصومه فغانی مهدی نیکبخت دستجردی منصور صالحی محمد ربانی اردشیر طالبی مهری فقیهی بهرام سلیمانی

چکیده ژن p53 به عنوان سرکوب کننده تومور، نقش مهمی در پایداری ژنومیک دارد. پلی مورفیسم g-to-c در کدون 72 از ژن p53 با افزایش خطر ابتلا به سرطان های ریه، نازوفارنکس، دهان، پروستات و کولورکتال ارتباط دارد و شاید بتوان آن را به عنوان مارکر استعداد ابتلا به سرطان پستان در نظر گرفت. این پژوهش، تأثیر این پلی مورفیسم ژن p53 بر کارسینومای مجرایی مهاجم پستان را بررسی نمود. روش ها: این مطالعه مورد-شاهدی ب...

2010
Peter L.J. de Keizer* Rémi-Martin Laberge* Judith Campisi

continues to surprise biologists. For nearly a decade, it was thought to be an oncogene [1, 2], only to be subsequently declared a potent tumor suppressor [3, 4]. Initially characterized as a transcriptional activator, we now know p53 is also a transcriptional repressor [5]. And just as it seemed p53 activities were confined to the nucleus, it became apparent that p53 also functioned in the cyt...

Journal: :journal of comprehensive pediatrics 0
kazunari kaneko department of pediatrics, kansai medical university, osaka, japan; department of pediatrics, kansai medical university, 2-5-1 shin-machi, hirakata-shi, p.o. box: 573-1010, osaka, japan. tel: +81-728040101-ext. 2560, fax: +81-728042758 ken yoshimura department of pediatrics, kansai medical university, osaka, japanسازمان اصلی تایید شده: 0 موسسات و مراکز خارج از کشور shoji tsuji department of pediatrics, kansai medical university, osaka, japanسازمان اصلی تایید شده: 0 دانشگاه های خارج از کشور

Journal: :journal of paramedical sciences 0
mitra behroozaghdam department of genetics, faculty of science, islamic azad university, science and research branch, tehran, iran. mehrdad hashemi department of genetics, islamic azad university, tehran medical sciences branch, tehran, iran. gholamreza javadi department of genetics, faculty of science, islamic azad university, science and research branch, tehran, iran. reza mahdian molecular medicine department, biotechnology research center, pasteur institute of iran, tehran, iran. mansoureh soleimani cellular and molecular research center, iran university of medical sciences, tehran, iran. zahra nadia sharifi department of anatomy, islamic azad university,tehran medical sciences branch,tehran,iran

mdma generally known as ecstasy, have deleterious effects on the serotonergic neurotransmitter system. recent findings suggest that the liver and brain are major target organs of mdma-related toxicities. although most research is being dynamically performed on brain, however, the molecular mechanisms by which mdma elicits adverse effects in both organs are poorly undrestood.the present study wa...

Journal: :iranian red crescent medical journal 0
mitra behroozaghdam department of genetics, faculty of sciences, sciences and research branch, islamic azad university, tehran, ir iran mehrdad hashemi department of genetics, tehran medical sciences branch, islamic azad university, tehran, ir iran; department of genetics, tehran medical sciences branch, islamic azad university, tehran, ir iran. tel: +98-2122006664, fax: +21-22008049 gholamreza javadi department of genetics, faculty of sciences, sciences and research branch, islamic azad university, tehran, ir iran reza mahdian molecular medicine department, biotechnology research center, pasteur institute of iran, tehran, ir iran mansoureh soleimani cellular and molecular research center, iran university of medical sciences, tehran, ir iran; department of anatomy, iran university of medical sciences, tehran, ir iran

background 3-4methylenedioxymethamphetamine (mdma) is a synthetic and psychoactive drug, which is known popularly as ecstasy and has toxic effects on human organs. objectives considering the potential toxic interaction, this study was performed to quantify the expression of bax and bcl2 genes in mdma-induced hepatotoxicity on rat liver. subsequently, we evaluated pentoxifylline as a possible pr...

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