نتایج جستجو برای: primary c3 deficiency
تعداد نتایج: 784306 فیلتر نتایج به سال:
Background: Complement Factor I (CFI) is a serine protease with an important role in complement alternative pathway regulation. Complete factor I deficiency is strongly associated with severe infections. Approximately 30 families with this deficiency have been described worldwide. Patients and methods: We have studied five new Spanish families suffering from CFI deficiency. From 19 screened peo...
BACKGROUND Complement Factor I (CFI) is a serine protease with an important role in complement alternative pathway regulation. Complete factor I deficiency is strongly associated with severe infections. Approximately 30 families with this deficiency have been described worldwide. PATIENTS AND METHODS We have studied five new Spanish families suffering from CFI deficiency. From 19 screened peo...
The Rho ADP-ribosylating C3 exoenzyme (C3bot) is a bacterial protein toxin devoid of a cell-binding or -translocation domain. Nevertheless, C3 can efficiently enter intact cells, including neurons, but the mechanism of C3 binding and uptake is not yet understood. Previously, we identified the intermediate filament vimentin as an extracellular membranous interaction partner of C3. However, uptak...
coincidence of autoimmune diseases such as immune thrombocytopenic purpura (itp) with immunodeficiencies has been reported previously in patients who suffered from primary antibody deficiency (pad). but there is no original study on immunological profiles of itp patients to find out their probable immune deficiency. in this case-control study, itp patients’ humoral immunity was investig...
Of the 30 distinct complement proteins recognized to date, C3 is probably the most versatile and multifunctional molecule known, interacting with at least 20 different proteins.'s2 It plays a critical role in both pathways of complement activation and participates in phagocytic and immunoregulatory processes.'V2 The study of C3 molecules from different species gives insight into the structural ...
search results show that numerous primary studies have been carried out in different parts of iran regarding prevalence of g6pd deficiency; if results of these studies are combined, a reliable estimation of prevalence of this factor will be achieved in iran. thus, present study, aimed to determine the prevalence of g6pd deficiency by combining findings of qualified primary studies using meta-an...
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