OBJECTIVE Addison's disease is frequently a component of autoimmune polyendocrinopathies while secondary adrenal insufficiency associated with autoimmune disorders is believed to be a rare event. We present a series of patients with secondary adrenal insufficiency coexisting with autoimmune diseases and/or antithyroid autoantibodies. DESIGN AND PATIENTS Among a group of 102 patients with seco...

Lymphoma may occasionally involve the adrenal glands, but primary adrenal lymphoma (PAL) is very rare and only few cases have been reported. We present a case of a 60-year-old, otherwise healthy, woman, with bilateral PAL presenting with adrenal insufficiency. The patient responded initially upon administration of large doses of intravenously hydrocortisone with total remission of symptoms. An ...

background: acute intoxication with alp is extremely lethal. the present study was conducted to determine the range of serum cortisol levels in alp poisoning and its correlation with patient outcome. methods: this study was carried out on patients who were intoxicated with alp. their demographic data and pertinent findings in their history and physical examination were recorded at the time of a...

The origin of the isolated secondary adrenal insufficiency is unknown in most cases. An observation of a group of over 100 patients with secondary adrenal insufficiency and coexisting autoimmune abnormalities suggests that autoimmunity could be a frequent cause of idiopathic secondary failure, similarly as in Addison's disease. We studied 176 patients with idiopathic isolated secondary adrenal ...

Primary Adrenal Lymphoma (PAL) is extremely rare and usually occurs in men the 6th-7th decade as bilateral, diffuse large B-cell lymphoma (DLBCL). Here, an 80-year-old patient admitted to urology outpatient clinic with flank pain bilateral adrenal mass detected on ultrasound presented. Positron Emission Tomography-Computed Tomography (PET-CT) was planned for who referred endocrine clinic. The P...

conclusions whenever a cushingoid appearance is accompanied by adrenal insufficiency, the exogenous use of steroids, especially topical creams, should be explored. hypertension may persist even after cessation of use and may result in life threatening complications. case presentation the present report describes the cases of three children and a 25-year-old man who presented with clinical featu...

BACKGROUND Auto-immune adrenal insufficiency is a potentially fatal disorder. Young women with spontaneous premature ovarian failure (POF) are at increased risk of developing this condition. METHODS We further characterized auto-immune adrenal insufficiency in this population by conducting an in-depth cross-sectional evaluation of adrenal function in a series of 123 women. RESULTS We uncove...

Addison’s disease is chronic primary adrenal insufficiency, a rare disorder which is characterized by adrenocortical insufficiency. The sign and symptom in Addison’s disease is nonspecific. This paper is to report Addison’s disease in a child focusing in diagnostic approach. Method is case report. Girl, 4 years old suffered from general weakness without paresthesia, fatigue, salt craving and hy...