AIM To investigate the pharmacokinetics and pharmacodynamics of single dose propacetamol in preterm and term infants on the first day of life. METHODS Neonates were stratified by gestational age. Preterm (< 37 weeks) and term (37-41 weeks) infants received a single dose of propacetamol in the first 24 hours of life when they had minor, painful procedures or as additional treatment in infants ...

OBJECTIVE Although there is an overall reduction in underfive mortality rate, the progress in reducing neonatal mortality rate has been very slow. Over the last 20 years, preterm births have steadily increased in low-income and medium-income countries (LMICs) particularly in sub-Saharan Africa and South Asia. Preterm birth is associated with increased mortality and morbidity, particularly in LM...

Preterm birth represents a high risk of neurodevelopmental disabilities when associated with white-matter damage. Recent studies have reported cognitive deficits in children born preterm without brain injury on MRI at term-equivalent age. Understanding the microstructural and metabolic underpinnings of these deficits is essential for their early detection. Here, we used diffusion-weighted imagi...

Retinopathy of prematurity (ROP) is a retinal disease that principally affects preterm neonates. It is recognized as the leading cause of preventable blindness and visual impairment in paediatric population, the major brunt of the disease affecting relatively immature newborns. An increase in survival of very young preterm infants, due to the advances in neonatology, have subjected them to the ...

Preterm labor is important in a predication of neonatal mortality. In united state of America it's relieved that the mortality rate of neonates has direct relation with frequency of low birth weight neonates and preterm labor. Neonates mortality and sever morbidity or both, before 26 th weeks of pregnancy occur in most of neonates and before 24 th. weeks of pregnancy occur approximately in all ...

BACKGROUND A patent ductus arteriosus (PDA) is frequently found in very preterm neonates and is associated with increased risk of morbidity and mortality. A shunt across a PDA can result in an unfavorable distribution of the cardiac output and may in turn result in poor renal perfusion. Urinary Neutrophil Gelatinase-associated Lipocalin (U-NGAL) is a marker of renal ischemia and may add to the ...

Background: QT dispersion (QTd) especially after ischemic heart disease and myocardial infarction is a prognostic predictor of mortality, in adult medicine.  Objective: This study was undertaken to determine the correlation between QT dispersion and neonatal stress. Neonates were divided into 3 groups: normal term (30 cases), normal preterm (30 cases) and sick neonates (36 cases), born between ...

Introduction  Preterm neonates are at risk of changes in their auditory system development, which explains the need for auditory monitoring of this population. The Auditory Steady-State Response (ASSR) is an objective method that allows obtaining the electrophysiological thresholds with greater applicability in neonatal and pediatric population. Objective  The purpose of this study is to compar...

Accepted 6 November 1995 Abstract Group B ,-haemolytic Streptococcus (GBS) may cause severe septic shock and death in neonates, whereas this is rarely the case in adults. As impaired red blood cell (RBC) deformability might disturb microcirculation in septic shock, the in vitro effects of GBS (1-7X108 cfu/ml) on RBC deformation (rheoscope) and haemolysis were studied in blood from preterm infan...

The concentrations of beta-lactoglobulin was measured in the sera of 47 preterm an term neonates during the first few days of life under standardised conditions after feeding with a cows' milk'based formula. Preterm neonates, particularly those of less than 33 weeks' gestation, had higher serum concentrations of beta-lactoglobulin than term neonates given an equivalent mild feed. Prior feeding ...