background: the major aneuploidies that are diagnosed prenatally involve the autosomal chromosomes 13, 18, and 21, as well as sex chromosomes, x and y. because multiplex ligation-dependent probe amplification (mlpa) is rapid and non-invasive, it has replaced traditional culture methods for the screening and diagnosis of common aneuploidies in some countries. objective:  to evaluate the sensitiv...

introduction: the most common chromosomal abnormalities detected in perinatal period are aneuploidies of chromosome 21, 18, 13, x and y. the aim of this study is to assess referral reasons for invasive diagnostic method using rapid qf-pcr for fetal chromosomal abnormalities in gynecologists’ referrals. methods: a retrospective study of results was performed on data between september 2015 and ju...

background: studies have shown that individuals with fertility problems experience psychosocial problems. the use of various coping strategies seems to have different impacts on women with infertility stress. the aim of this study was to examine the role of coping strategies (active-avoidance, passive-avoidance, active-confronting and meaning based) in predicting infertility stress among a grou...

OBJECTIVE According to the dual-process theory, coping flexibility is defined as the ability to produce and implement a new coping strategy in place of an ineffective coping strategy. Specifically, coping flexibility includes two processes: evaluation coping and adaptive coping. Evaluation coping refers to sensitivity to feedback about the efficacy of a coping strategy, and adaptive coping invo...

how to cite this article: javadzadeh m. prenatal diagnosis and genetic counseling for niemann-pick c disease. iran j child neurol. 2015 autumn;9:4(suppl.1): 22.   pls see pdf.

conclusions at present, no single diagnostic procedure is able to cause damage to the embryo or fetus. there are possible harmful effects for doses above 0.2 - 0.25 gy (20-25 rad). context many women of reproductive age and pregnant women require diagnostic tests involving ionizing radiation. fetal exposure to radiation worries both the patient and the obstetricians and could lead to inappropri...

neonatal ovarian cysts (noc) are usually self-limiting structures, however, large or complex cysts may lead to severe complications. unfortunately, no standard guidelines have been introduced for the management, treatment and follow-up of these cysts. in this report, we aimed to introduce a very large noc without any pre- and post-natal complications. a 30 year-old mother, gravida 2, para 2, wi...

background evaluation of the cerebellum and vermis is one of the integral parts of the fetal cranial anomaly screening. objectives the aim of this study was to create a nomogram for fetal vermis measurements between 17 and 30 gestational weeks. patients and methods this prospective study was conducted on 171 volunteer pregnant women between march 2013 and december 2014. measurements of the feta...

in previous years, identification of fetal cells in maternal blood circulation has caused a new revolution in non-invasive method of prenatal diagnosis. low number of fetal cells in maternal blood and long-term survival after pregnancy limited the use of fetal cells in diagnostic and clinical applications. with the discovery of cell-free fetal dna (cffdna) in plasma of pregnant women, access to...