The manner in which menstruation, femininity and the role of the mother are perceived, along with the social influences, are emphasized in the psychosocial dimension of premenstrual syndrome. This study attempts to investigate the perception of mothers and attitudes toward menstruation of a group of women diagnosed with premenstrual dysphoric disorder (PMDD) in a secular Muslim country. Thirty ...

Madam I am somewhat concerned that in the same issue of the Journal as the statistical paper entitled ‘Size does matter’1 there was an Overview on ‘Homeopathy treatments for premenstrual symptoms’2 which may be considered to have depended on evidence that contradicted the statistical paper. I would be grateful for your opinion as to the reliability of the one clinical trial by Yakir et al.3, wh...

A 34-year-old woman has a diagnosis of bipolar disorder type I (BDI) and is currently euthymic on 7 mg daily of aripiprazole. A comorbid diag nosis of premenstrual dysphoric disorder (PMDD) was confirmed with 2 months of prospective charting. She was initiated on an oral contraceptive (estradiol 30 mcg plus levonorgestrel 0.15 mg daily), and after 6 weeks of treatment she noted substantial impr...

Premenstrual syndromes (PMS) are a group of menstrually related, chronic and cyclical disorders characterized by emotional, behavioral, and physical symptoms in the second half (luteal phase) of the menstrual cycle. Several line of evidence point to a significant role of the serotonergic system in the course of the luteal phase in women with PMS/ Premenstrual Dysphoric Disorder. It has been rep...

The treatment of premenstrual dysphoric disorder (PMDD) is far from satisfactory, as there is a high proportion of patients who do not respond to conventional treatment. The antidiuretic sulfonamide, acetazolamide, inhibits carbonic anhydrase and potentiates GABAergic transmission; the latter is putatively involved in PMDD. We therefore tried acetazolamide in a series of women with intractable ...

BACKGROUND Studies show that selective serotonin reuptake inhibitors are effective for severe premenstrual syndrome and premenstrual dysphoric disorder. This study compares the efficacy of a selective serotonin reuptake inhibitor with that of a tricyclic antidepressant to determine whether efficacy for premenstrual syndrome/premenstrual dysphoric disorder is a general or more serotonergic effec...