BACKGROUND Magnetoencephalography (MEG), a noninvasive technique for evaluation of epileptic patients, records magnetic fields during neuronal electrical activity within the brain. Anaesthesia experience for MEG has not yet been reported. METHODS We retrospectively reviewed records of 48 paediatric patients undergoing MEG under anaesthesia. Thirty-one patients (nonprotocol group) were managed...

Sir,—Jones and Drummond (1981) have shown that premedication with atropine does not influence the frequency of postoperative respiratory complications. However, they do not nuke a recommendation for routine use, or otherwise, of atropine in premedicatioa. Studies on the effects of atropine administration on ciliary activity have shown conflicting results. Experimental studies in dogs have not s...

OBJECTIVES To investigate whether a 360-degree horizontal turn after oral premedication with simethicone improves the mucosal visibility during gastroendoscopic examination, and to determine the proper time to turn over the patient. METHODS This study involved 993 patients scheduled for gastroendoscopy. Just before gastroendoscopy, after oral premedication with simethicone, patients were rand...

www.chestpubs.org those receiving placebo. However, after adjusting for age, sex, smoking history, bronchoscopic biopsy, procedure time, operator experience, and baseline hemodynamic variables and oxygen saturation, the use of anticholinergic premedication was associated with signifi cantly lower airway secretions as reported by the bronchoscopist. Because excessive airway secretions are rarely...

THE concept and practice of pre-anaesthetic medication were introduced by Claude Bernard (1869) and Labbe and Goujon (1872) who administered morphine before inducing anaesthesia with chloroform. A few years later Schafer (1880) and Dastre and Morat (1884) recommended giving atropine as well as morphine. Scopolamine was first used by Schneiderlin (1903) and papaveretum (Omnopon) by Leipoldt (191...

The preoperative effects of oral oxypertine have been compared with those of papaveretum and atropine in 185 patients in a double-blind between-patient study. Oxypertine 20 mg given orally as a nocturnal sedative and again on the morning of operation produced relief of anxiety comparable to that of papaveretum 10 mg and atropine 0.6 mg. It is concluded that oxypertine may be of value in medicat...

A double-blind random study compared the effects of lorazepam and pantopon an intra-muscular premedication in healthy women for uterine curettage (D & C). Anxiety, as assessed by a self-rating test by the patient and by a trained observer, showed a significant reduction at one and one-half hours after lorazepam and a smaller reduction after pantopon, which was not significant. Sedation was sati...

Sublingual triazolam 0.2 mg (T) was compared with peroral diazepam 10 mg (D) as a premedicant in a randomised, double-blind study. Eighty-one ASA I-III patients aged 18-70 yr, scheduled for elective surgery and general anaesthesia were studied. The patients were premedicated about one hour preoperatively. The T-group subjects (n = 41) received triazolam sl after a placebo po and the D-group sub...

Melatonin possesses sedative, hypnotic, analgesic, antiinflammatory, antioxidative, and chronobiotic properties that distinguish it as an attractive alternative premedicant. A qualitative systematic review of the literature concerning the perioperative use of melatonin as an anxiolytic or analgesic in adult patients was carried out using the recommended guidelines provided by the Cochrane Handb...