Prediction of protein structures from protein sequences using computers is an important step to discover proteins' 3D conformation structures and their functions and hence has profound theoretical and practical significance in areas such as protein engineering and drug design. In this talk, we will discuss our new results in protein secondary structure and Transmembrane protein prediction using...

This dissertation consists of three essays in microeconomic theory. The first two focus on how to elicit information about the state of the world from strategic agents, either to make a decision or for its own sake. The third studies a model of decentralized two-sided matching markets. In “Mechanisms for making accurate decisions in biased crowds”, I study decision rules for finding the true an...

Let M (f) denote the midpoint rule and T (f) the trapezoidal rule for estimating ∫ b a f(x) dx. Then Simpson’s rule = M (f) + (1 − )T (f), where = 3 . We generalize Simpson’s rule to multiple integrals as follows. Let Dn be some polygonal region in R; let P0; : : : ; Pm denote the vertices of Dn, and let Pm+1 equal the center of mass of Dn. De4ne the linear functionals M (f) =Vol(Dn)f(Pn+1), wh...

introduction: acute coronary syndrome accounts for more than 15% of the chest pains. recently, hess et al. developed north american chest pain rule (nacpr) to identify very low-risk patients who can be safely discharged from emergency department (ed). the present study aimed to validate this rule in eds of two academic hospitals. methods: a prospective diagnostic accuracy study was conducted on...

Rule-based and information-integration category learning were compared under minimal and full feedback conditions. Rule-based category structures are those for which the optimal rule is verbalizable. Information-integration category structures are those for which the optimal rule is not verbalizable. With minimal feedback subjects are told whether their response was correct or incorrect, but ar...

An analytical method for predicting elastic–plastic stress distribution in a cylindrical pressure vessel has been presented. The vessel material was a ceramic/metal functionally graded material, i.e. a particle–reinforcement composite. It was assumed that the material’s plastic deformation follows an isotropic strain-hardening rule based on the von-Mises yield criterion, and that the vessel was...