Focusing on ionophore-based ion-selective electrodes (ISEs), this work highlights recent advances in increasing sensor sensitivity by converting potentiometric response to a variety of electrical and optical signals including charge, current, luminescence, color change.

The observed reference ranges for sodium and potassium as determined by direct potentiometry vary from instrument to instrument, depending on the composition of the calibration standards. To resolve the existing confusion as to which reference intervals are most appropriately considered "normal," we propose a straightforward convention (based on plasma-water concentration units) in which the di...

Strategies to facilitate detection enhancement in various methods of nitrate detection are presented in this paper. The main nitrate detection methods for the past 10 years will be reviewed according to their advantages and disadvantages, followed by a focus on the techniques on increasing detection capabilities. For each detection method, an investigation of the technique of improvement is car...