background: the organizational environment and its existing context may deeply affect on empowerment of individuals. in educational institutions as well as other organizations, students are going to be powerful when opportunities for growth and achievement of power are provided for them in learning and educational environments. this study has been carried out to explain the facilitators and imp...

the objective of present research was to design, evaluate and compare drug release from two different dosage forms in pulsatile drug delivery system (dds) for metoprolol tartarate (mt) as tablet and capsule. pulsatile systems are gaining a lot of interest as they deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal delivery ...

objective(s): we aimed to investigate the influence of transient receptor potential channel 3 (trpc3) on lipopolysaccharide-induced (lps) preterm delivery mice. materials and methods: mice were randomly assigned to the four groups: an unpregnant group, a mid-pregnancy group (e15), a term delivery group, and an lps-induced preterm delivery group (intraperitoneal injection lps at 15 days). uterin...

background prematurity is an issue related to increasing the neonatal morbidity and mortality and smoking pregnant women cause the risk of low birth weight and prematurity increase, compared to non-smoking ones. results of all 205 women, 43 (20.97%) women exposed to shs during pregnancy and 162 (79.02%) women did not. in shs exposure group, 11 infant (25.6%) and in non- shs exposure group, 17 i...

glioma, as a primary tumor of central nervous system, is the main cause of death in patients with brain cancer. therefore, development of an efficient strategy for treatment of glioma is worthy. the aim of the current study was to develop a srl peptide-coated dendrimer as a novel dual gene delivery system for targeting the lrp receptor, an up-regulated gene in both bbb and glioma cells. to perf...

objective polyethylenimine (pei), a readily available synthetic polycation which has high transfection efficiency owing to its buffering capacity was introduced for transfection a few years ago. but it has been reported that pei is cytotoxic in many cell lines. in this study, in order to enhance the transfection efficiency of 10 kda pei and reduce its toxicity, hydrophobic residues were grafted...

nowadays, developements in nanotechnology have leeds an increased application of this newborn technology in cancer treatment. in this study, a stabilized micelle was developed to load hpd in order to be used in photodynamic treatment of cancer in an animal model. to construct micelles, pluronic p-105 was used and stabilized to encapsulate hpd . this process includes a 24 h polymerization in whi...

background : high incidence of menstrual disorders at late ages of fertility accounts for 20% of clinical visits and 25% of gynecological surgeries. this study was conducted to identify the relationship between delivery type and menstrual disorders in women referring to hospitals affiliated to medical universities in tehran in 2008. methods : in this case-control study, which was conducted from...

Diagenesis in the Permo-Triassic New Red Sandstone, Isle of Arran is characterized by early cementation hematite, clay, and calcite minerals, followed burial compaction, quartz, feldspar, pyrite cementation. Cataclasis post-dated quartz feldspar reduced grain pore aperture size deformed samples. Samples with cataclastic bands typically have 18% porosity 8.81 mD permeability on average. Whereas,...