Protein arginine methylation is a widespread post-translational modification (PTM) in eukaryotic cells. This chemical proteins functionally modulates diverse cellular processes from signal transduction, gene expression, DNA damage repair,...
Journal:
:The International journal of developmental biology2011
Christopher J HindleyGary S McDowellHelen WiseAnna Philpott
The developing embryo is patterned by a complex set of signals and interactions resulting in changes in cell division, cell fate determination and differentiation. An increasing body of evidence points to the role of the ubiquitin proteasome system (UPS) and ubiquitin-mediated protein degradation as a major mechanism of protein regulation, crucial for control of developmental processes. The spe...
