A female one month old with features supporting a diagnosis of neonatal progeroid syndrome(WRS)  presented to our neonatology section of GB pant children hospital Srinagar .she had prenatal and post natal growth failure, generalized lipotrophy, triangular face, psedohydrocephalous, sparse scalp hair and eye brows, prominent scalp veins and greatly widened anterior fontenella.

Neonatal seizures are amongst the most common neurologic conditions managed by a neonatal care service. Seizures can exacerbate existing brain injury, induce "de novo" injury, and are associated with neurodevelopmental disabilities in post-neonatal life. In this mini-review, we present evidence in support of the use of ganaxolone, a GABAA agonist neurosteroid, as a novel neonatal therapy. We di...

Cole, A. P., and Hargreaves, T. (1972). Archives of Disease in Childhood, 47, 415. Conjugation inhibitors and early neonatal hyperbilirubinaemia. Milk and serum were obtained from 50 mothers on the 6th day post partum and examined for inhibitory activity against bilirubin conjugation in rat liver slices. Neonatal serum bilirubin levels were also analysed at this time. There was no relation betw...

A 30-year-old pregnant woman had skin lesions at 38 weeks of gestation. She was diagnosed as primary varicella zoster infection. Her clinical symptoms were high fever and generalized vesicles eruption. No serious maternal complication was found. The patient delivered a male baby 4 days after she developed skin lesions. The neonatal blood IgM against varicella zoster was negative. The baby was g...

Neonatal Care is one specialty within nursing as a whole where the repertoire of skills and knowledge for practice is broad. Competence in skills, an important component of today's nursing agenda, must extend to any post-basic specialty a nurse opts to work within. To become 'qualified in specialty' (QIS) is an aim of nurses who work within the neonatal area of practice following qualification,...

in this paper we report a case of jejunal atresia that was detected pre-nataly. polyhydramnios and multiple dilated bowel loops in the lower part of fetal abdomen in ulterasonography helped us to diagnose this abnormality. post-natal barium enema showed it and also it was confirmed by laparotomy confirmed it. pre-natal diagnosis is important in these cases to facilitate delivery in centers wher...

19 Infraorbital nerve (ION) transection in neonatal rats leads to disruption of whisker20 specific neural patterns (barrelettes), conversion of functional synapses into silent 21 synapses and reactive gliosis in the brainstem trigeminal principal nucleus (PrV). Here 22 we tested the hypothesis that neonatal peripheral nerve crush injuries permit better 23 functional recovery of associated centr...

Intranasal treatment with C57BL/6 MSCs reduces lesion volume and improves motor and cognitive behavior in the neonatal hypoxic-ischemic (HI) mouse model. In this study, we investigated the potential of human MSCs (hMSCs) to treat HI brain injury in the neonatal mouse. Assessing the regenerative capacity of hMSCs is crucial for translation of our knowledge to the clinic. We determined the neuror...

RATIONALE Studies have demonstrated that exosomes can repair cardiac tissue post-myocardial infarction and recapitulate the benefits of cellular therapy. OBJECTIVE We evaluated the role of donor age and hypoxia of human pediatric cardiac progenitor cell (CPC)-derived exosomes in a rat model of ischemia-reperfusion injury. METHODS AND RESULTS Human CPCs from the right atrial appendages from ...

Neonatal cholestasis is a prolonged elevation of the serum levels of conjugated bilirubin beyond the first 14 days of life. Commonest etiologies include extrahepatic conditions like biliary atresia, intrahepatic like congenital malformations, infections and inborn errors of metabolism. TORCH infections constitute 22% cases of neonatal hepatitis, of which Cytomegalovirus is the commonest agent. ...