The target range of a bacterial secretion system can be defined by effector substrate specificity or by the efficacy of effector delivery. Here, we report the crystal structure of Tse1, a type VI secretion (T6S) bacteriolytic amidase effector from Pseudomonas aeruginosa. Consistent with its role as a toxin, Tse1 has a more accessible active site than related housekeeping enzymes. The activity o...

In order to develop antimicrobial mixtures which provide broad-spectrum antimicrobial activity for use with cultured cell autografts, several individual antimicrobial agents, in concentrations non-toxic for cells in culture, were tested against a variety of bacteria and Candida spp. isolated from burn patients. An agar well diffusion topical assay was used. Antimicrobials active against Gram-po...

background & aim: nowadays, the application of traditional medicine and herbal medicinal plants instead of chemical and synthetic drugs has captured the attention of the researchers. the purpose of this study was to investigate the antimicrobial effects of the aquatic, ethanolic and methanolic (80%) extracts of the aerial and root parts of stachys lavandulifolia vahl which were taken from t...

biotics having low toxicity and high activities against both Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and Gram-negative bacteria including Pseudomonas aeruginosa (P. aeruginosa), which are the main bacteria causing nosocomial infections, are now urgently required. Recently, we introduced cefoselis (CFSL)4'5), which shows potent broadspectrum activity a...

BACKGROUND Medicinal plants are widely used for the treatment of different infectious diseases. Infectious diseases caused by bacteria have a large impact on public health. This study aimed to determine the in vitro antibacterial activity of the medicinal plants traditionally used in Vietnam against the bacterial strains associated with infectious diseases. METHODS Methanol extracts of twelve...

OBJECTIVES Respiratory infections with multidrug-resistant (MDR) bacteria are life-threatening in patients with cystic fibrosis (CF). Squalamine and aminosterol derivatives (ASDs) have previously demonstrated interesting antibacterial activity against bacterial reference strains. This study investigated for the first time their activity against MDR clinical isolates recovered from the sputa of ...

BACKGROUND The study randomly screened leaf extracts of several hundred southern African tree species against important microbial pathogens to determine which taxa have the highest activity and may yield useful products to treat infections in the animal health market. METHODS We determined the antibacterial and antifungal activity of 714 acetone leaf extracts of 537 different tree species aga...

In this study, the antimicrobial activity of crude extracts of flower, fruit, stem and leaf of Conocarpus erectus and purified tannins were evaluated against three fungi and seven Gram-positive, Gram-negative and acid-fast bacteria. While, by disc diffusion method, extracts of different parts of C.erectus were active only against Saccharomyces cerevisiae, purified tannins were active against Sa...

PURPOSE The aim of this study was to determine the microbiology of primary acquired nasolacrimal duct obstruction (PANDO) and its antimicrobial susceptibilities. METHODS Ninety-three patients (100 eyes) diagnosed with PANDO, categorized as acute, chronic dacryocystitis, or simple epiphora, were prospectively enrolled. Lacrimal sac contents were cultured for aerobic and anaerobic bacteria and ...

How to cite this article: Journal of Advanced Materials, 2017,1, 1: 23-30 ABSTRACT Evaluation of antimicrobial activity with Ciprofloxacin (C) (control of antibacterial study) and ketoconazole (K) (control antifungal activity) compounds released from chitosan based composites [(A1 (CS/PVP/fMWCNT) A2 (CS/PVP/f-MWCNT-GLU)] against gram positive bacteria and gram negative have been studied. The in...