Journal:
:iranian journal of radiation research
0
m. aghili department of radiotherapy oncology, cancer institute, tehran university of medical sciences, tehran, iran
m. babaei department of radiotherapy oncology, cancer institute, tehran university of medical sciences, tehran, iran
m. ganjalikhani tehran university of medical sciences, tehran, iran
f. azmoodeh ardalan department of central pathology, imam khomeini hospital, tehran university of medical sciences, tehran, iran
background: in recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. in this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...