The Study was carried out at Department of Sericulture, UAS, GKVK, Bengaluru under irrigated condition during the 2020-21 to study effect soil application liquid organic manures in mulberry and its on larval cocoon traits silkworm, V-1 variety planted 90+150 × 60 cm spacing. Three different were tested against recommended dose fertilizer (control), leaf quality assessed via feeding silkworm. Si...

The domesticated silkworm, Bombyx mori serves as an ideal representative of lepidopteran species for a variety of scientific studies. As a result, databases have been created to organize information pertaining to the silkworm genome that is subject to constant updating. Of these, four main databases are important for store nucleotide information in the form of genomic data, ESTs and microsateli...

Establishment of efficient genome editing tools is essential for fundamental research, genetic engineering, and gene therapy. Successful construction and application of transcription activator-like effector nucleases (TALENs) in several organisms herald an exciting new era for genome editing. We describe the production of two active TALENs and their successful application in the targeted mutage...

Nuclear polyhedrosis, that is jaundice, is distinguished among other mulberry silkworm diseases by its pathogenicity. It is a powerful viral, hereditary disease of mulberry silkworm that results in mass destruction of mulberry silkworm. Polyhedrose is spread in all silk manufacturer countries and incurs the losses to sericulture more than any infectious diseases of mulberry silkworm. Viruses wh...

Ganciclovir, foscarnet, vidarabine and ribavirin, which are used to treat viral infections in humans, inhibited the proliferation of a baculovirus (Bombyx mori nucleopolyhedrovirus) in BmN4 cells, a cultured silkworm cell line. These antiviral agents inhibited the proliferation of baculovirus in silkworm body fluid and had therapeutic effects. Using the silkworm infection model, the antiviral a...

The present study has been aimed at examining severe perturbations in the Cholinergic system in different tissues like Silk Gland, Hemolymph, Fat body and Muscle of silkworm larvae treated with Zinc, vitamin, Pyridoxine and hormone, Methoprene. The experimental worms were divided in to four groups and fed with mulberry leaves soaked in the selected compounds i.e. Zinc chloride, Pyridoxine, Meth...

The silkworm extract powder contain 1-deoxynojirimycin (DNJ), a potent α-glycosidase inhibitor, has therapeutic potency against diabetes mellitus. Therefore, natural products containing DNJ from mulberry leaves and silkworm are consumed as health functional food. The present study was performed to evaluate the safety of the silkworm extract powder, a health food which containing the DNJ. The re...

Although the 30K family proteins are important anti-apoptotic molecules in silkworm hemolymph, the underlying mechanism remains to be investigated. This is especially the case in human vascular endothelial cells (HUVECs). In this study, a 30K protein, 30Kc6, was successfully expressed and purified using the Bac-to-Bac baculovirus expression system in silkworm cells. Furthermore, the 30Kc6 expre...

Catecholamine metabolism plays an important role in the determination of insect body color and cuticle sclerotization. To date, limited research has focused on these processes in silkworm. In the current study, we analyzed the interactions between catecholamines and melanin genes and their effects on the pigmentation patterns and physical properties of sclerotized regions in silkworm, using the...

The development of a spider silk-manufacturing process is of great interest. However, there are serious problems with natural manufacturing through spider farming, and standard recombinant protein production platforms have provided limited progress due to their inability to assemble spider silk proteins into fibers. Thus, we used piggyBac vectors to create transgenic silkworms encoding chimeric...