Wound healing is a complicated, multistep process involving many cell types, growth factors and compounds(1-3). Because of this complexity, wound healing studies are most comprehensive when carried out in vivo. There are many in vivo models available to study acute wound healing, including incisional, excisional, dead space, and burns. Dead space models are artificial, porous implants which are...

PURPOSE To evaluate the size and shape of commercially available polyvinyl alcohol (PVA) particles and to determine whether they change in size when suspended in nonionic contrast and in a solution of nonionic contrast and absolute alcohol. METHODS The two-dimensional area and the long and short axis of PVA particles from several different vendors were measured using a light microscope attach...

Previous reports have claimed Adriamycin to be cytotoxic to cultured tumor cells when the drug is covalently immobilized on a solid support, thus suggesting a cell surface mechanism of action for the drug. Although these previous reports attempted to rule out released drug or endocytosis of drug-support particles as alternative explanations for the observed cytotoxicity, a more thorough analysi...

PURPOSE We aimed to evaluate the therapeutic effect and safety of transarterial embolization using bleomycin-iodinated oil and polyvinyl alcohol particles for the treatment of symptomatic hepatic focal nodular hyperplasia (FNH). METHODS This retrospective study included 23 consecutive patients with symptomatic hepatic FNH, who underwent embolization using bleomycin-iodinated oil and polyvinyl...