Many cell adhesion molecules have a distinct pattern of expression and well-defined role in cell-cell recognition. In contrast, NCAM is broadly expressed and perturbations of its function affect many diverse aspects of embryonic development Evidence has been obtained suggesting that the molecule and its polysialic acid moiety serve not only to contribute to specific interactions , but also to r...

Recently, M. Dmitrova et al. (Mol. Gen. Genet. 257:205-212, 1998) described a LexA-based genetic system to monitor protein-protein interactions in an Escherichia coli background. However, the plasmids used in this system, pMS604 and pDP804, were not readily amenable for general use. In this report, we describe modifications of both plasmids that allow fragments of DNA to be fused to either vect...

....................................................................................... 2 Acknowledgements ........................................................................... 4 Statement of original contributions .............................................. 5 List of abbrevations ...................................................................... 6 Table of contents ..................