نتایج جستجو برای: polyoclonal antibody
تعداد نتایج: 166396 فیلتر نتایج به سال:
background: infection is now the most common cause of morbidity in systemic lupus erythematosus (sle). there is lack of information regarding the specific antibody forma-tion in response to vaccines in young sle patients. objective: to determine the efficacy of anti-tetanus antibody response in young patients with sle. methods: forty sle pa-tients with mean age of 14.1 years (range: 7-21) and 6...
background: preeclampsia (pe) is a pregnancy specific syndrome that is associated with high maternal and fetal morbidity and mortality. glucose regulated protein78 (grp78) is an endoplasmic reticulum (er) protein which is expressed on the cell surfaces of trophoblast cells under stress or hypoxic condition. grp78 has a role in aggressive behavior of invasive cells and may play a role in normal ...
background hepatitis b virus (hbv) infection is a major public health problem that affects billions of people worldwide. the lack of information on hbv prevalence among the general population is an obstacle to formulate effective policies to reduce the burden of viral hepatitis. objectives this population based serological survey was conducted in kermanshah province to determine the local preva...
Background and purpose: Antibody phage display library is a powerful in vitro technology for production of recombinant antibody fragments against a wide variety of antigens. However, the presence of insert-free clones in the phage libraries limited the specific enrichment of antibody fragments in many studies. The aim of this study was to protein A-aided recovery of insert-containing phages in ...
we have employed a peptide-based antibody generation protocol for producing antibody against human nestin. using a 12-mer synthetic peptide from repetitive region of human nestin protein devoid of any n- or o-glyco-sylation sequences, we generated a mouse monoclonal antibody capable of recognizing human, mouse, bovine, and rat nestin. a wide variety of nestin proteins ranging from 140-250 kda w...
Recent major antibody deals involve immune checkpoint inhibitors, antibody–drug conjugates and natural killer cell engagers for cancer.
Background: Human plasminogen is a plasma glycoprotein synthesized mainly in the liver. Conversion of plasminogen to plasmin by plasminogen activators is a key event in the fibrinolytic system. In this study, we investigated the effects of two anti-human plasminogen monoclonal antibodies, A1D12 and MC2B8 on Glu-plasminogen activation in presence of u-PA, t-PA and streptokinase. Methods: Produci...
background: inhibitory antibody to exogenous factor viii (fviii) is a major complication of hemophilia treatment. this study was conducted to determine the prevalence of inhibitor antibody directed against fviii.methods: from may 2010 to may 2011, 52 patients with severe hemophilia a admitted in amirkola children’s hospital were evaluated. those who had abnormal mixing study, antibody against f...
Background and Aim: Hashimoto's thyroiditis is the most prevalent cause of hypothyroidism in children and adults. The disease clinically manifests itself in three forms namely hypothyroidism, euthyroidism, and hyperthyroidism. The present study was carried out aiming at determining anti-thyroid peroxidase antibody variation before and after levothyroxine treatment in hashimoto's thyroiditis pat...
Background and Objective: Rh (Rhesus) is a highly complex blood group system in man which plays an important role in transfusion medicine. The aim of this study was the isolation of RhD protein from the membrane of RBCs. Materials and Methods: In this experimental study immunoprecipitation method with human anti-RhD polyclonal antibody was utilized for the isolation of RhD antigen from Rh+ huma...
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