The formation of polymeric micelles by the self-association of diblock copolymers consisting of hydrophilic and hydrophobic segments in aqueous medium is currently a topic of great interest. This interest is motivated by the attractive applications of polymeric micelles to various research areas such as drug delivery carrier technology and nanotechnology. In the biomedical materials field, poly...

X-ray computed tomography (XCT) provides a volumetric map of a specimen in three dimensions, generated from a set of radiographs. Due to the speed and quality of measurement, XCT systems with cone beam geometry and matrix detectors have become widely used. Continuous improvements in the quality and performance of Xray tubes and devices have led to cone beam XCT systems which can now achieve spa...

Purpose: To evaluate physicochemical changes in ciprofloxacin following incorporation in Carbopol polymeric composites. Methods: The ciprofloxacin and Carbopol were mixed in water in a drug:polymer ratio of 1:5 (w/w) and homogenized to produce uniform composites. X-ray powder diffraction analysis of the pure ciprofloxacin and the Carbopol polymeric composites of the drug were obtained using a p...

Polymeric nanoparticle is a general platform for drug delivery that has been receiving extensive attention in both academia and industry. With the ability to load drugs at high encapsulation efficiency, to release drugs at a sustained and controllable manner, and to be functionalized with targeting agents for cell-specific drug delivery, polymeric nanoparticle-based drug formulations show great...

Micropatterned composite membranes of polymerized and fluid lipid bilayers were constructed on solid substrates. Lithographic photopolymerization of a diacetylene-containing phospholipid, 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine (DiynePC), and subsequent removal of nonreacted monomers by a detergent solution (0.1 M sodium dodecyl sulfate (SDS)) yielded a patterned polymeric bil...

Chemical sensors are generally based on the integration of suitable sensitive layers and transducing mechanisms. Although inorganic porous materials can be effective, there is significant interest in the use of polymeric materials because of their easy fabrication process, lower costs and mechanical flexibility. However, porous polymeric absorbents are generally amorphous and hence present poor...

nanoparticles classified in 4 overall groups containing: metallic nanoparticles, ceramic nanoparticles, polymeric nanoparticles and semiconductor nanoparticles. these nanoparticles are used in some biomedical applications such as carrying medicine and photographing agents. with attention to different criteria which are both qualitative and quantitative, selecting the most suitable nanoparticles...

Am. J. Enol. Vitic. 56:3 (2005) 197 Phenolic compounds are important to red wine quality because they impact color, mouthfeel, and ageability. Although phenolics are present in grape juice, the amount is greatly increased in wine because of their greater solubility in ethanol than in purely aqueous solutions. Typical levels of the major grape phenolics present in red wine are shown in Table 1. ...

PURPOSE The cornea is a main barrier to drug penetration after topical application. The aim of this study was to evaluate the abilities of micelles generated from a positively charged triblock copolymer to penetrate the cornea after topical application. METHODS The triblock copolymer poly(ethylene glycol)-poly(ε-caprolactone)-g-polyethyleneimine was synthesized, and the physicochemical proper...

In relation to recent advances in nanobiotechnologies, cancer-targeted therapy using nano-scaled drug carriers (nanocarriers) has been attracting enormous attention with success in clinical studies. Polymeric micelles, core-shell-type nanoparticles formed through the self-assembly of block copolymers, are one of the most promising nanocarrier, because their critical features such as size, stabi...