background and objective: the effect of opioids on the reproductive system has been studied as an attractive research field. in this study, the effect of morphine as an analgesic opioid was evaluated on the ovarian polycystic induction in the rat. materials & methods: in this study, 24 female virgin wistar rats weighing 200-250 g were injected with morphine (1-10 mg/kg/day) for 9 days. cont...

The aim of this study was to determine basal serum vascular endothelial growth factor (VEGF) concentrations and Doppler blood flow changes within the ovarian stroma of women with polycystic ovaries (PCO) and women with normal ovaries. Pulsed and colour Doppler blood flows within the ovarian stroma were recorded, and serum VEGF concentrations measured, in the early follicular phase (days 2-3 of ...

Background: Polycystic ovary syndrome (PCOS) is an endocrine disturbance that causes primary anovulation that result in infertility. There are more symptoms accompanying this syndrome: acne, hirsutism, obesity, irregular menstrual cycle and many others. This syndrome can be more or less successfully treated but in 10-15% of cases it is resistant to any kind of treatment used in nowadays practic...

The prevalence of polycystic ovaries (PCO) and polycystic ovary syndrome (PCOS) in the general population is approximately 20 and 10%, respectively, and published studies suggest a similar prevalence in women with epilepsy. These data do not suggest that epilepsy is associated with a higher prevalence of the condition, and it would appear that the background prevalence of PCO and PCOS is the sa...

Background and Objective: Morphine can cause harmful effects in the ovaries. The silver nanoparticles (Ag-NPs) used in health care because of antimicrobial properties, can diffuse into the brain blood barrier. This study investigated the protective effect of Ag-NPs on the induction of polycystic ovary (PCO) due to injection of morphine intra-ventromedial hypothalamus (intra-VMH) of rat compared...

The polycystic ovary syndrome (originally called the Stein–Leventhal syndrome), was popularized by the two Americans whose names have been attached to the condition for 70 years (Stein and Leventhal 1935), and was considered as a problem of anovulation and infertility. They described their treatment of anovulation using wedge resection with remarkable success. However as medical treatment becam...

Oocyte in vitro maturation (IVM) is an assisted reproductive technology in which oocytes are retrieved from the antral follicles of unstimulated or minimally stimulated ovaries. IVM of human oocytes has emerged as a promising procedure. This new technology has advantages over controlled ovarian stimulation such as reduction of costs, simplicity, and elimination of ovarian hyperstimulation syndr...

OBJECTIVES To review different clinical endocrine manifestation of polycystic ovarian syndrome in adolescent girls. METHODS A descriptive study was conducted in Holy Family Hospital, Rawalpindi, Pakistan from Nov 2001 to Oct 2002. Adolescent girls diagnosed with polycystic ovaries on ultrasound seen in the out patients department for menstrual problems were included in the study. Their body m...