in this study, porous scaffolds from poly(d,l-lactic acid) have been prepared via liquid- liquid phase separation method in ternary system of polymer-1,4-dioxane-water. polymer dissolved in dioxane in 1.5, 2.5 and 5 % wt/v and the solvent/non-solvent ratios were 13/87, 15/85 and 17/83. cloud point curves prepared by visual turbidometry. in order to obtain porous scaffolds with inter-connected p...

lysozyme, as a model protein, was precipitated through the formation of protein-zn complex to micronize for subsequent encapsulation within poly (lactic-co-glycolic acid) (plga) microspheres. various parameters, including ph, type and concentration of added salts and protein concentration, were modified to optimize the yield of protein complexation and precipitation. the resulting protein parti...

The development of scaffolds for tissue-engineered growth the anterior cruciate ligament (ACL) is a promising approach to overcome limitations current solutions. This work proposes novel biodegradable and biocompatible matching mechanical characteristics native human ligament. Poly(L-lactic acid) (PLA) reinforced with graphite nano-platelets (PLA+EG) as received, chemically functionalized (PLA+...

This article reports experimental data related to the research article entitled "Poly(malic acid-co-l-lactide) as a Superb Degradation Accelerator for Poly(l-lactic acid) at Physiological Conditions" (H.T. Oyama, D. Tanishima, S. Maekawa, 2016) [1]. Hydrolytic degradation of poly(l-lactic acid) (PLLA) blends with poly(aspartic acid-co-l-lactide) (PAL) and poly(malic acid-co-l-lactide) (PML) oli...

Poly(vinyl alcohol) and poly(vinyl pyrrolidone) were blended and films were obtained by casting method. Glutaraldehyde, hydrochloric acid and lactic acid were added to investigate their effect on mechanical properties, swelling and solubility of the blends with the aim to find a possible material candidate for medium or long term implants. Combination of all three additives (lactic acid, glutar...

OBJECTIVE Dental caries is an infectious disease that can be prevented in several ways. The aim of this study was to compare the efficacy of sodium fluoride mouthrinse and nano- hydroxyapatite (nano-HA) for the remineralization of incipient caries. MATERIALS AND METHODS After obtaining different concentrations of nano-HA (0-2-5-10%), 60 sound premolars fixed in acrylic blocks were coated with...

Now a day there is an emerging interest in replacing non-renewable additives with biodegradable compounds. Cellulose plays very important role in this modification. Their low cost and low density associated with high specific mechanical properties represent a good renewable and biodegradable alternative to the most commonly used synthetic reinforcement. The cellulose was modified by using 2-(Tr...

A novel sponge composed of a poly (lactic acid) composite skeleton covered with bonelike apatite (b-HA) was produced via a particleleaching technique combined with a biomimetic processing. The sponge has a large porosity of w75% with large-sized pores and shows mechanical ductility. After incubation of human osteoblasts for 7 days, numerous cells attached to the surface of the skeleton, which w...