Objective: This study was conducted to determine the clinical characteristics and differential diagnosis of individual cases acute flaccid paralysis (AFP) reporting tertiary care teaching hospital Jaipur. Methods: prospective observational among patients attending outdoor, indoor, neurology clinics with provisional AFP. The based on available data, vaccination status, laboratory results (stool ...

The recent report of an explosive outbreak of poliomyelitis in an orphanage in Delhi(l) and the subsequent correspondence(2,3) have highlighted the phenomenon of 'provocation poliomyelitis'. If an intramuscular injection is given during silent poliovirus infection, paralysis may set in within a day or two. In a community in which poliovirus circulation is intensive, children are at increased ri...

Acute paralytic poliomyelitis is still prevalent inspite of large scale immunization programmes being carried out throughout the country. One of the important factors incriminated to provoke paralysis is administration of intramuscular (IM) injections especially, when the child has had exposure to poliovirus(l). IM injections are commonly prescribed in cases of fever(2). The relationship of par...

There have been many investigations on the uptake of radioactive phosphorus by viral infected cells (1, 2), but the number of studies in which cells of animal origin are employed are few. To our knowledge, there are no studies on the effects of poliomyelitis virus on phosphorus metabolism in the HeLa cell. However, this cell has been successfully infected by the poliomyelitis virus (3, 4). In t...

Abstract We aimed to analyze the trend of indicators National Immunization Program (acronym in Portuguese. PNI) children under one-year-old and classify municipalities regarding risk transmission vaccine-preventable diseases (RTVPD) Maranhão from 2010 2021. This ecological time series study was based on secondary data vaccination coverage (VC). homogeneity (VCH). proportion abandonment (PA). RT...

OBJECTIVE To describe the characteristics of compatible poliomyelitis cases and to assess the programmatic implications of clusters of such cases in India. METHODS We described the characteristics of compatible poliomyelitis cases, identified clusters of compatible cases (two or more in the same district or neighbouring districts within two months), and examined their relationship to wild pol...

The virus of poliomyelitis is neurotropic, and localizes, and probably is capable of multiplying in the extramedullary parenchymatous nervous organs. It has been demonstrated by inoculation tests in the intervertebral, Gasserian, and abdominal sympathetic ganglia. All the ganglia show histological lesions, more or less severe, similar to those of the spinal cord and brain. The severest occur in...