Germline cell fate is specified by localized OSK, VAS and other components in the pole plasm of the Drosophila embryo. New work shows that a PIWI-mediated miRNA pathway contributes to this process by regulating OSK and VAS localization.

Vasa, a DEAD box mRNA helicase similar to eIF4A, is involved in pole plasm assembly in the Drosophila oocyte and appears to regulate translation of oskar and nanos mRNAs. However, several vasa alleles exhibit a wide range of early oogenesis phenotypes. Here we report a detailed analysis of Vasa function during early oogenesis using novel as well as previously identified hypomorphic vasa alleles...

Pole side impact crash tests are in use in regulatory and consumer programs around the world. There is some diversity in the test methods that are applied, including the suitability of available side impact dummies for use in these tests. For the WorldSID 50 percentile adult male dummy, much theoretical discussion has focussed on the likely rib response, including the direction of this response...

The creativity research community is in search of a viable cognitive measure providing support for behavioral observations that higher ideational output is often associated with higher creativity (known as the equal-odds rule). One such measure has included divergent thinking: the production of many examples or uses for a common or single object or image. We sought to test the equal-odds rule u...

® The contents of this report reflect the views of the authors, who are responsible for the facts and the accuracy of the information presented herein. This document is disseminated under the sponsorship of the Department of Transportation University Transportation Centers Program, in the interest of information exchange. This project evaluates the physical and economic feasibility of using exi...

The telomere bouquet, i.e., telomere clustering on the nuclear envelope (NE) during meiotic prophase, is thought to promote homologous chromosome pairing. Using a visual screen, we identified bqt2/im295, a mutant that disrupts telomere clustering in fission yeast. Bqt2p is required for linking telomeres to the meiotic spindle pole body (SPB) but not for attachment of telomeres or the SPB to the...

We used video-light microscopy and laser microsurgery to test the hypothesis that as a bioriented prometaphase chromosome changes position in PtK1 cells, the kinetochore moving away from its associated pole (AP) exerts a pushing force on the centromere. When we rapidly severed congressing chromosomes near the spindle equator between the sister kinetochores, the kinetochore that was originally "...

A variable reluctance machine (VRM) has been proven to be an outstanding candidate for electric vehicle (EV) applications. This paper introduces a new double-stator, 12/14/12-pole three-phase hybrid-excited modular variable reluctance machine (MVRM) for EV applications. In order to demonstrate the superiorities of the proposed structure, the static torque characteristics and dynamic performance...