BACKGROUND Spontaneous resolution of Pneumocystis jirovecii pneumonia has rarely been reported. CASE REPORT A 59-year-old man presented to our hospital because of pyrexia (38°C) and shaking chills for 2 days. He had a history of right nephrectomy due to renal cell carcinoma and left upper lobectomy for lung metastasis in the last 1.5 years. Two months previously, he was treated with oral pred...

Seventy five patients with pulmonary disease and suspected acquired immune deficiency syndrome (AIDS) underwent fibreoptic bronchoscopy with bronchoalveolar lavage. Of 54 cases of Pneumocystis carinii pneumonia, 53 (98%) were diagnosed by bronchoalveolar lavage. Complications were recorded in 12 instances and included pneumothorax in two and transient increase in fever and hypoxaemia in the rem...

Invasive pulmonary aspergillosis (IPA) and pneumocystis jiroveci pneumonia (PCP) are life-threatening opportunistic infections that occur in immunocompromised hosts. Early diagnosis and treatment of these opportunistic infections is essential to the survival of immunocompromised patients. We report a 60-year-old man undergoing short-term steroid therapy after surgical resection of a brain tumor...

Pneumocystis jirovecii causes pneumonia in immunosuppressed individuals. However, it has been reported the detection of low levels of Pneumocystis DNA in patients without signs and symptoms of pneumonia, which likely represents colonization. Several studies performed in animals models and in humans have demonstrated that Pneumocystis induces a local and a systemic response in the host. Since P ...

background and objectives: pneumocystis jiroveci is an important causative agent of pneumocystis pneumonia. during childhood, exposure to pneumocystis occurs and antibody was built in early childhood. the aim of this study was to describe the molecular epidemiology of p. jiroveci in children without any respiratory syndrome and survey the distribution of different mitochondrial large subunit, r...

Pneumocystis pneumonia remains a common opportunistic infection in the diverse immunosuppressed population. One clear risk factor for susceptibility to Pneumocystis is a declining CD4(+) T cell count in the setting of HIV/AIDS or primary immunodeficiency. Non-HIV-infected individuals taking immunosuppressive drug regimens targeting T cell activation are also susceptible. Given the crucial role ...

Pneumocystis was first described in 1909 as an evolutionary phase in the life cycle of Trypanosoma cruzi by Chagas [1]. Later it was defined as a different organism [2]. Pneumocystis pathogenesis in humans was shown in 1951 for the fist time [3]. Recently, a species of Pneumocystis which afflicts humans was named Pneumocystis jiroveci [4]. Pneumocystis pneumonia (PCP) has remained as one of the...

BACKGROUND AND PURPOSE Pneumocystis pneumonia, caused by Pneumocystis jirovecii, is a fatal disease threatening patients with AIDS or immunosuppression. Assessment of colonization in these patients is of great significance, since it can lead to severe pulmonary disorders. Considering the scarcity of published reports on Pneumocystis jirovecii isolates from patients in Mashhad, Iran, we aimed to...

Although unusual, focal upper zone air space opacification and cyst formation in Pneumocystis carinni pneumonia and HIV infection can occur and may mimic "classical" tuberculosis. (Thorax 1993;48:869-870) Pneumocystis carinii pneumonia (PCP) is the most common HIV related pulmonary infection in both Great Britain and the USA. We report a patient with upper zone opacification and cavitatory dise...