Pasteurella multocida causes various diseases in a broad range of wild and domestic animals. Toxigenic strains of the serotypes A and D produce an AB protein toxin named Pasteurella multocida toxin (PMT). PMT constitutively activates the heterotrimeric G protein subunits Gαq, Gα13, and Gαi through deamidation of a glutamine residue, which results in cytoskeletal rearrangements as well as increa...

Recanalization therapy is controversial in patients with acute stroke due to terminal internal carotid artery (ICA) occlusion. A 78-year-old man underwent successful percutaneous transarterial microsnare-assisted thrombectomy (PMT) for the treatment of acute terminal ICA occlusion, which was recanalized completely. This case report suggests that PMT is a potential treatment for patients with ac...

The dermonecrotic toxins from Pasteurella multocida (PMT), Bordetella (DNT), Escherichia coli (CNF1-3), and Yersinia (CNFY) modulate their G-protein targets through deamidation and/or transglutamination of an active site Gln residue, which results in activation of the G protein and its cognate downstream signaling pathways. Whereas DNT and the CNFs act on small Rho GTPases, PMT acts on the α su...

The light gains of a detector system (PMT and scintillator) is characterized by the number photoelectrons produced per unit energy (usually MeV). In this study, results gain tests for 10 Hamamatsu R11833 model photomultiplier tubes (PMT) are shown. Various radioactive sources were used in conjunction with EJ309 liquid scintillator to determine gain. was determined comparing size signal generate...

BACKGROUND Bovine congenital pseudomyotonia (PMT) is an impairment of muscle relaxation induced by exercise preventing animals from performing rapid movements. Forms of recessively inherited PMT have been described in different cattle breeds caused by two independent mutations in ATP2A1 encoding a skeletal-muscle Ca2+-ATPase (SERCA1). We observed symptoms of congenital PMT in four related Romag...

Tc-99m PMT and Tc-99m GSA can be taken up by hepatocellular carcinoma (HCC), but there has been no report concerning HCC showing accumulation of both of Tc-99m PMT and Tc-99m GSA. In this paper we describe a case of two simultaneously developed HCCs, one of which took up both tracers but the other took up neither of them.

An important problem in multiresolution analysis of signals and images consists in restoring continuous hidden random variables x = {xs}s∈S from observed ones y = {ys}s∈S . This is done classically in the context of Hidden Markov Trees (HMT). HMT have been generalized recently to Pairwise Markov Trees (PMT). In this paper we propose a smoothing restoration algorithm for Gaussian PMT.

BACKGROUND The results of a recently performed randomized clinical trial showed that the effect of a multidisciplinary treatment of chronic pain patients on body awareness (BA), catastrophizing, and depression was improved by adding psychomotor therapy (PMT), an intervention targeting BA. No significant effects were found on quality of life and disability. The present follow-up study aimed to e...