نتایج جستجو برای: platelet index

تعداد نتایج: 502894  

Journal: :Arteriosclerosis, thrombosis, and vascular biology 1995
H Moriwaki M Matsumoto N Handa Y Isaka K Hashikawa N Oku M Nakamura T Kamada T Nishimura

We examined the relation between in vivo thrombogenicity and the morphology of carotid lesions to clarify the role of platelet deposition in carotid atherothrombosis. We evaluated 60 subjects (120 carotid bifurcations) who had at least one established risk factor for atherosclerosis by using indium 111 platelet scintigraphy and high-resolution B-mode ultrasonography. We evaluated platelet accum...

Journal: :Haematologica 2016
Ben Johnson Gillian C Lowe Jane Futterer Marie Lordkipanidzé David MacDonald Michael A Simpson Isabel Sanchez-Guiú Sian Drake Danai Bem Vincenzo Leo Sarah J Fletcher Ban Dawood José Rivera David Allsup Tina Biss Paula Hb Bolton-Maggs Peter Collins Nicola Curry Charlotte Grimley Beki James Mike Makris Jayashree Motwani Sue Pavord Katherine Talks Jecko Thachil Jonathan Wilde Mike Williams Paul Harrison Paul Gissen Stuart Mundell Andrew Mumford Martina E Daly Steve P Watson Neil V Morgan

Inherited thrombocytopenias are a heterogeneous group of disorders characterized by abnormally low platelet counts which can be associated with abnormal bleeding. Next-generation sequencing has previously been employed in these disorders for the confirmation of suspected genetic abnormalities, and more recently in the discovery of novel disease-causing genes. However its full potential has not ...

Ebadollah Ssalek Moghadam, Fatemeh Abbasi, Mojgan Pourmokhtar, Nasrin Zarei,

Background: Platelet preparations have been used for a wide variety of clinical applications such as hemorrhage, tissue engineering and cellular therapy. Platelet concentrates can be prepared by the apheresis method or from the whole blood using the Buffy-coat or Platelet-rich plasma methods. The purpose of this study was to compare four variations of platelet-rich plasma method based on double...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2009
O Schreiber J Petersson M Phillipson M Perry S Roos L Holm

Recent findings indicate that dextran sodium sulfate (DSS)-induced colitis is associated with a prothrombogenic phenotype, with P-selectin playing a major role in platelet recruitment. It has been suggested that probiotics may ameliorate colonic inflammation. We therefore investigated how treatment with Lactobacillus reuteri influenced P-selectin expression, leukocyte and platelet endothelial c...

Journal: :Archivos de cardiologia de Mexico 2016
Martha Eva Viveros Carlos Areán Sergio Gutiérrez Soledad Vázquez Mario Humberto Cardiel Alejandra Taboada Gissela Marín Ruben Solorio Nalley García

OBJECTIVE Drug inhibition of platelet P2Y12 adenosine diphosphate receptor has reduced the incidence of adverse cardiovascular events after percutaneous coronary interventions. The analysis of the phosphorylation status of vasodilator-stimulated phosphoprotein by flow cytometry has shown a predictive value for adverse events and stent thrombosis. Polymorphisms of CYP2C19 in high risk patients m...

Journal: :Annals of hepatology 2013
Angelo Zambam de Mattos Angelo Alves de Mattos Larissa Faraco Daros Maiara Isabel Musskopf

BACKGROUND & AIMS Variceal bleeding is a dramatic and common complication of cirrhosis, and, therefore, endoscopy is recommended for the screening of EV (esophageal varices) in every cirrhotic. This study evaluates the capacity of APRI (aspartate aminotransferase-to-platelet ratio index) in non-invasively predicting EV. MATERIAL AND METHODS This cross-sectional study evaluated cirrhotics for ...

2016
Mohammed Mukhtar Fayez Hafez Sameer Fatani Abdullatif Babakr Ahmed Fawzy

Hepatic fibrosis; chronic hepatitis C; HCV genotype 4; serum hyaluronic acid (HA); serum Collagen type IV (Coll-IV); AST to platelet ratio index (APRI) and Receiver operating characteristics

Journal: :Gut 1992
I Sobhani S Hochlaf Y Denizot C Vissuzaine E Rene J Benveniste M M Lewin M Mignon

Platelet activating factor (PAF-ACETHER or PAF) and precursors of platelet activating factor were investigated in 26 patients with acute Crohn's disease and in 10 healthy controls. Platelet activating factor, lyso platelet activating factor, and alkyl acyl glycerophosphocholine, were determined in colonic mucosal biopsies in patients with acute Crohn's disease, during prednisolone therapy, and ...

Journal: :Mediators of Inflammation 2008
Dorit Samocha-Bonet Dan Justo Ori Rogowski Nili Saar Subchi Abu-Abeid Galina Shenkerman Itzhak Shapira Shlomo Berliner Aaron Tomer

OBJECTIVE In this work we studied the correlation between platelet count, platelet activation, and systemic inflammation in overweight, obese, and morbidly obese individuals. METHODS AND SUBJECTS A total of 6319 individuals participated in the study. Complete blood counts, high sensitivity C-reactive protein (hs-CRP) serum levels, and body mass index (BMI) were measured during routine checkup...

Journal: :Psychosomatic medicine 2005
Erica C Bruce Dominique L Musselman

Platelets, the smallest corpuscular component of human blood, are central to various crucial biologic pathways in the human body. Diminished platelet function is thought to contribute to the increased risk of ischemic heart disease in patients with major depressive disorder, and to the increased morbidity and diminished survival of depressed patients after an index myocardial infarction. We rev...

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