Platelets contain a reservoir of growth factors that have numerous biological activities such as assisting in chemotaxis, cell differentiation, proliferation, and angiogenesis which all are pivotal the wound healing process. From this, platelet concentrates been described literature beginning from first generation to second both beneficial impact on soft hard tissue following oral surgical proc...

Prophylactic platelet concentrates transfusion represents a therapeutic choice in patients with chemotherapy-induced thrombocytopenia. This prospective, non-interventional study evaluated the effects of platelet concentrates transfusion on thromboelastometric parameters of platelet function in 36 transfusion occasions for 11 thrombocytopenic children undergoing chemotherapy. Pre- and posttransf...

Autologous platelet concentrates are successfully adopted in a variety of medical fields to stimulate bone and soft tissue regeneration. The rationale for their use consists in the delivery of a wide range of platelet-derived bioactive molecules that promotes wound healing. In addition, antimicrobial properties of platelet concentrates have been pointed out. In this study, the effect of the pla...

To measure pH in platelet concentrates, blood gas analysers with different calibration principles may be used. In this study, variances observed in pH measurements with two types of blood gas analysers were investigated. pH was measured in crystalloid solutions (platelet additive solution (PAS-II), phosphate-buffered solutions) and two types of platelet concentrates (containing 100% plasma, or ...

BACKGROUND Each year, millions of platelet transfusions save the lives of cancer patients and patients with bleeding complications. However, between 10 and 30% of all platelet transfusions are clinically ineffective as measured by corrected count increments, but no test is currently used to identify and avoid these transfusions. ThromboLUX(®) is the first platelet test intended to routinely cha...

Platelet concentrates can be stored for five days at 22 C. Our objective was to increase the storage of platelets to 7 days by decreasing the storage temperature. Lower temperature may minimize chances of bacterial proliferation and also maintain platelet functions to optimum level. The study sample iincluded 25 blood donors of both sex in State Blood Bank, Chhatrapati Shahuji Maharaj Medical U...

Platelet concentrates are universally prepared with a standard method and stored for 5 days at room temperature (20-24°C) in gentle agitation. Currently, there is a renewed interest in the possibility of storing platelet concentrates below the standard temperatures. In fact, cold platelets might be more effective in bleeding patients and have a lower risk of bacterial transmission. Inventories ...