Colistin methanesulfonate (CMS), the inactive prodrug of colistin, is administered by inhalation for the management of respiratory infections. However, limited pharmacokinetic data are available for CMS and colistin following pulmonary delivery. This study investigates the pharmacokinetics of CMS and colistin following intravenous (i.v.) and intratracheal (i.t.) administration in rats and deter...

it has been shown that, in overdense plasmas of the type encountered in spherical tori, electron Bernstein waves can be excited in a plasma by mode conversion of either an externally launched X mode or an O mode. The electron Bernstein waves are strongly absorbed by electrons in the region where the wave frequency matches the Doppler broadened electron cyclotron resonance frequency or its harmo...

The decomposition of trichloroethylene (TCE) by non-thermal plasma was investigated in a dielectric barrier discharge (DBD) reactor with a copper rod inner electrode and compared with a plasma-catalytic reactor. The particularity of the plasma-catalytic reactor is the inner electrode made of sintered metal fibers (SMF) coated by transition metal oxides. In order to optimize the geometry of the ...

BACKGROUND Impaired antioxidant defenses are implicated in neurodegenerative disease. The plasma levels of urate, a water-soluble antioxidant, are reduced in Alzheimer's disease (AD). OBJECTIVE We aimed to test the hypotheses that high plasma urate at baseline is associated with: (1) a reduced rate of conversion from mild cognitive impairment (MCI) to AD and (2) a lower rate of cognitive decl...

The plasma concentration, production rate, and conversion ratio of androstenedione and testosterone were studied in seven children with congenital adrenal hyperplasia (CAH) of the 21-hydroxylase type. Plasma androstenedione and testosterone measured by double isotope derivative assay and estimated blood production rates were manyfold increased in the untreated state, markedly suppressed with gl...

Global warming, along with increasing global energy demands, has led to the need for a sustainable and low-carbon-based economy. In addition renewable technologies, such as biomass, solar, hydro, wind, another possible strategy mitigate climate change is capture/conversion recycling of CO2. recent years, many methods both CO2 capture (mainly adsorption, absorption, membrane) conversion (many el...

For the first time, experiments were carried out on decomposition of carbon dioxide in a plasma torch maintained by continuous focused gyrotron radiation with frequency 263 GHz an argon flow at atmospheric pressure. It is shown that, despite decrease electron density factor 5, when 3% added to plasma-forming gas, it possible achieve its degree conversion 22% due nonequilibrium nature maintainin...

Anthropogenic greenhouse gas emissions have caused changes to the Earth’s climate, resulting in catastrophic weather events that are becoming more frequent and intense. Developing carbon-neutral processes for CO2 conversion powered by renewable energy is one way of attaining a circular economy, as waste converted new carbon-containing product, without also being created by-product during proces...