Objectives The purpose of this study was the automated generation and validation of parametric blood flow velocity maps, based on contrast-enhanced ultrasound (CEUS) scans. Materials and Methods Ethical approval for animal experiments was obtained. CEUS destruction-replenishment sequences were recorded in phantoms and three different tumor xenograft mouse models. Systematic pixel binning and ...

Regular monitoring of expanding impervious surfaces areas (ISAs) in urban areas is highly desirable. MODIS data can meet this demand in terms of frequent observations but are lacking in spatial detail, leading to the mixed land cover problem when per-pixel classifications are applied. To overcome this issue, this research develops and applies a spatio-temporal sub-pixel model to estimate ISAs o...

OBJECTIVES The aim of this study was to evaluate fully quantitative myocardial blood flow (MBF) at a pixel level based on contrast-enhanced first-pass cardiac magnetic resonance (CMR) imaging in dogs and in patients. BACKGROUND Microspheres can quantify MBF in subgram regions of interest, but CMR perfusion imaging may be able to quantify MBF and differentiate blood flow at a much higher resol...

The authors review the theoretical basis of determination of cerebral blood flow (CBF) using dynamic measurements of nondiffusible contrast agents, and demonstrate how parametric and nonparametric deconvolution techniques can be modified for the special requirements of CBF determination using dynamic MRI. Using Monte Carlo modeling, the use of simple, analytical residue models is shown to intro...

Background Myocardial edema is usually assessed by T2W Turbo Spin Echo (TSE), using either Triple Inversion Recovery (STIR) or Double Inversion Recovery (DIR) with spectral fat saturation. Both TSE sequences have important drawbacks, such as low SNR when using the body coil, dropout of the lateral wall signal and use of semi-quantitative analysis by computing the ratio of myocardial to skeletal...

The performance of pixel modules built from 75 μm thin silicon sensors and ATLAS read-out chips employing the Solid Liquid InterDiffusion (SLID) interconnection technology is presented. This technology, developed by the Fraunhofer EMFT, is a possible alternative to the standard bump-bonding. It allows for stacking of different interconnected chip and sensor layers without destroying the already...

A many-key chaotic image encryption scheme based on the Lorenz system is presented. Using the time-delay Lorenz system, the proposed approach performed the pixel permutation on a bit-by-bit basis in the diagonal and antidiagonal directions, providing the necessary pixel confusion. Then, the Lorenz system is employed again to generate a sequence of random bytes that are used in the diffusion ste...