Basal cell carcinoma (BCC) is the most frequent type of skin cancer in humans. Non-pigmented BCCs are much more prevalent than pigmented BCCs. Sometimes it could be difficult to distinguish a pigmented BCC from a melanoma [1]. Menzies et al. suggested a dermatoscopic method with a sensitivity of 93% and a specificity of 89% for diagnosing pigmented BCCs (See Table) [2,3]. The correct answer to ...

Background: Actinic dermatitis is an environmental skin disease resulting from excessive exposure to ultraviolet light irradiated by the sun. This phototoxic reaction affects dogs and cats, particularly with short hair lightly pigmented skin, exposed sun light. Primary lesions are typical a sunburn chronic exposure, may induce premalignant lesion known as actinic keratosis, which develop neopla...

Dermoscopy, in expert hands, increases accuracy, sensitivity and specificity in diagnosis of pigmented skin lesions of a single operator, compared with clinical examination. Simplified algorithmic methods have been developed to help less expert dermoscopists in diagnosis of melanocytic lesions. This study included 125 melanocytic skin lesions divided into melanocytic nevi, dysplastic nevi and t...

Various benign and malignant non-melanocytic tumors, including skin appendage tumors, sometimes accompany non-neoplastic melanocytes, and this phenomenon has been described as “melanocytic colonization” [1-7]. Porocarcinoma is a rare skin appendage carcinoma related to the sweat gland duct, originally described by Pinkus and Mehregan in 1963 [8]. Its incidence is reported to be 0.004% of skin b...

The quantification of skin carotenoid levels has a range of applications in Caucasian populations, from serving as a versatile and noninvasive biomarker (e.g., of systemic carotenoid levels, carotenoid consumption, the antioxidative capacity of skin, and oxidative stress) to being used in appearance-based interventions. Yet, no study has investigated the quantitative effect of carotenoid supple...

We previously developed a quantitative autoradiographic tech nique with special forceps for measuring unscheduled DNA synthesis (UDS) in mouse skin after treatment with ultraviolet light in vivo. By this method, we investigated the relationship between the protective role of melanin and UV-induced DNA repair in black-and-white guinea pigs. Flat areas containing a sharp border between pigmented ...

We previously developed a quantitative autoradiographic technique with special forceps for measuring unscheduled DNA synthesis (UDS) in mouse skin after treatment with ultraviolet light in vivo. By this method, we investigated the relationship between the protective role of melanin and UV-induced DNA repair in black-and-white guinea pigs. Flat areas containing a sharp border between pigmented a...