Photoinduced cross-linking (PIC) has become a powerful tool in chemical biology for the identification and mapping of stable or transient interactions between biomacromolecules and their (unknown) ligands. However, the value of PIC for in vitro and in vivo structural proteomics can be realized only if cross-linking reports accurately on biomacromolecule secondary, tertiary, and quaternary struc...

A novel Immersed-Finite-Element Particle-in-Cell (IFE-PIC) simulation tool is presented in this paper for plasma surface interaction where charged plasma particles are represented by a number of simulation particles. The Particle-in-Cell (PIC) method is one of the major particle models for plasma simulation, which utilizes a huge number of simulation particles and hence provides a first-princip...

A polyelectrolyte ionomer complex (PIC) composed of cationic and anionic polymers was developed for nanomedical applications. Here, a poly(ethylene glycol)-poly(lactic acid)-poly(ethylene imine) triblock copolymer (PEG-PLA-PEI) and a poly(aspartic acid) (P[Asp]) homopolymer were synthesized. These polyelectrolytes formed stable aggregates through electrostatic interactions between the cationic ...

In pancreatic β-cells, glucose-induced mitochondrial ATP production plays an important role in insulin secretion. The mitochondrial phosphate carrier PiC is a member of the SLC25 (solute carrier family 25) family and transports Pi from the cytosol into the mitochondrial matrix. Since intramitochondrial Pi is an essential substrate for mitochondrial ATP production by complex V (ATP synthase) and...

Clustering is a group of objects that are similar among themselves but dissimilar to objects in other clusters. Clustering large dataset is a challenging task and the need for increase in scalability and performance formulates it to use parallelism. Though the use of Big Data has become very essential, analyzing it is demanding. This paper presents the (pC-PIC) parallel Client based Power Itera...

This paper presents a recently developed particle simulation code package PIFE-PIC, which is novel three-dimensional (3-D) parallel immersed finite element (IFE) particle-in-cell (PIC) model for simulations of plasma-material interactions. framework based on the nonhomogeneous electrostatic IFE-PIC algorithm, designed to handle complex interface conditions associated with irregular geometries u...

This paper explores the feasibility of Tierra-based OBC that evolves programs through a bit inversion caused by Single-Event Upset. In particular, Tierra-based OBC is applied to the evolution of the PIC assembly programs. Additionally, this paper proposes a new method that can reliably recover the broken program to the correct one. Intensive experiments reveal that (1) Tierra-based OBC cannot o...

This paper describes a new technique for improving the performance of multistage parallel interference cancellation (PIC) multiuser detection. The focus of the paper is on the hard-decision multistage PIC detector due to the fact that it possesses two desirable properties: (a) very low computational complexity in binary communication systems and (b) the optimum (joint maximum likelihood) bit es...

This paper presents the PIC matrices, a computationally efficient subclass of link matrices that may be considered for the interpretation of query operators in the INQUERY inference network. The PIC class of matrices is formally defined; a algorithm, PIC-EVAL, is presented for the evaluation of members of this class; and a proof of the correctness of the algorithm is given. A further specializa...

We assess the quantitative accuracy of the particle-in-cell (PIC) approximation used in recent ab initio predictions of the thermodynamic properties of hexagonal-closepacked iron at the conditions of the Earth’s inner core. The assessment is made by comparing PIC predictions for a range of thermodynamic properties with the results of more exact calculations that avoid the PIC approximation. It ...