The function GrpSeqBnds computes efficacy and futility boundaries given the stipulation of the information fraction, total type I and type II error probabilities and method of boundary construction. The efficacy and futility boundaries can be constructed either simulataneously or one at a time. The function also allows for two information scales. The following sequence of variance fractions res...

extract: sever coughs of the little zahra who has 8 months old informed you even before that her parents inter to the ward. zahra's developmental needs in terms of emotional, physical and social will required a detailed cares in her hospitalization period. but at this time her breathing problem may attracted your attention. needs and differences of the mentioned infant explain below. zahra...